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Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia

Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore,...

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Published in:BMC pregnancy and childbirth 2024-07, Vol.24 (1), p.512-7, Article 512
Main Authors: Belete, Debaka, Fekadie, Engidayehu, Kassaw, Melkamu, Fenta, Melaku, Jegnie, Azanu, Mulu, Tigist, Adane, Gashaw, Abebe, Wondwossen, Amare, Azanaw
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creator Belete, Debaka
Fekadie, Engidayehu
Kassaw, Melkamu
Fenta, Melaku
Jegnie, Azanu
Mulu, Tigist
Adane, Gashaw
Abebe, Wondwossen
Amare, Azanaw
description Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia. A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software. In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women. In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration.
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Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia. A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software. In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women. In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. 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subjects Adolescent
Adult
Age
Antigens
Blood & organ donations
Data collection
Ethiopia
Ethiopia - epidemiology
Female
Guhala
Hepacivirus - immunology
Hepatitis B
Hepatitis B - blood
Hepatitis B - epidemiology
Hepatitis B - transmission
Hepatitis B Surface Antigens - blood
Hepatitis B virus
Hepatitis B virus - immunology
Hepatitis C
Hepatitis C - blood
Hepatitis C - epidemiology
Hepatitis C - transmission
Hepatitis C Antibodies - blood
Hepatitis C virus
Hospitals
Humans
Infections
Infectious Disease Transmission, Vertical - statistics & numerical data
Laboratories
Liver cancer
Liver cirrhosis
Medical personnel
Mothers
Population
Pregnancy
Pregnancy Complications, Infectious - blood
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Pregnant women
Prenatal Care
Prevalence
Public health
Retrospective Studies
Seroepidemiologic Studies
Serology
Womens health
Young Adult
title Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia
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