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Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia
Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore,...
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Published in: | BMC pregnancy and childbirth 2024-07, Vol.24 (1), p.512-7, Article 512 |
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description | Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia.
A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software.
In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women.
In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration. |
doi_str_mv | 10.1186/s12884-024-06714-6 |
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A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software.
In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women.
In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration.</description><identifier>ISSN: 1471-2393</identifier><identifier>EISSN: 1471-2393</identifier><identifier>DOI: 10.1186/s12884-024-06714-6</identifier><identifier>PMID: 39075410</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Adolescent ; Adult ; Age ; Antigens ; Blood & organ donations ; Data collection ; Ethiopia ; Ethiopia - epidemiology ; Female ; Guhala ; Hepacivirus - immunology ; Hepatitis B ; Hepatitis B - blood ; Hepatitis B - epidemiology ; Hepatitis B - transmission ; Hepatitis B Surface Antigens - blood ; Hepatitis B virus ; Hepatitis B virus - immunology ; Hepatitis C ; Hepatitis C - blood ; Hepatitis C - epidemiology ; Hepatitis C - transmission ; Hepatitis C Antibodies - blood ; Hepatitis C virus ; Hospitals ; Humans ; Infections ; Infectious Disease Transmission, Vertical - statistics & numerical data ; Laboratories ; Liver cancer ; Liver cirrhosis ; Medical personnel ; Mothers ; Population ; Pregnancy ; Pregnancy Complications, Infectious - blood ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Complications, Infectious - virology ; Pregnant women ; Prenatal Care ; Prevalence ; Public health ; Retrospective Studies ; Seroepidemiologic Studies ; Serology ; Womens health ; Young Adult</subject><ispartof>BMC pregnancy and childbirth, 2024-07, Vol.24 (1), p.512-7, Article 512</ispartof><rights>2024. The Author(s).</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c445t-72e41c90db1a0afc9af66f6c258a49dc7f3acdf655d9ece2d8d13f9830b665af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285531/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3091291610?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39075410$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Belete, Debaka</creatorcontrib><creatorcontrib>Fekadie, Engidayehu</creatorcontrib><creatorcontrib>Kassaw, Melkamu</creatorcontrib><creatorcontrib>Fenta, Melaku</creatorcontrib><creatorcontrib>Jegnie, Azanu</creatorcontrib><creatorcontrib>Mulu, Tigist</creatorcontrib><creatorcontrib>Adane, Gashaw</creatorcontrib><creatorcontrib>Abebe, Wondwossen</creatorcontrib><creatorcontrib>Amare, Azanaw</creatorcontrib><title>Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia</title><title>BMC pregnancy and childbirth</title><addtitle>BMC Pregnancy Childbirth</addtitle><description>Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia.
A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software.
In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women.
In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Antigens</subject><subject>Blood & organ donations</subject><subject>Data collection</subject><subject>Ethiopia</subject><subject>Ethiopia - epidemiology</subject><subject>Female</subject><subject>Guhala</subject><subject>Hepacivirus - immunology</subject><subject>Hepatitis B</subject><subject>Hepatitis B - blood</subject><subject>Hepatitis B - epidemiology</subject><subject>Hepatitis B - transmission</subject><subject>Hepatitis B Surface Antigens - blood</subject><subject>Hepatitis B virus</subject><subject>Hepatitis B virus - immunology</subject><subject>Hepatitis C</subject><subject>Hepatitis C - blood</subject><subject>Hepatitis C - epidemiology</subject><subject>Hepatitis C - transmission</subject><subject>Hepatitis C Antibodies - blood</subject><subject>Hepatitis C virus</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious Disease Transmission, Vertical - statistics & numerical data</subject><subject>Laboratories</subject><subject>Liver cancer</subject><subject>Liver cirrhosis</subject><subject>Medical personnel</subject><subject>Mothers</subject><subject>Population</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - blood</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Pregnancy Complications, Infectious - virology</subject><subject>Pregnant women</subject><subject>Prenatal Care</subject><subject>Prevalence</subject><subject>Public health</subject><subject>Retrospective Studies</subject><subject>Seroepidemiologic Studies</subject><subject>Serology</subject><subject>Womens health</subject><subject>Young Adult</subject><issn>1471-2393</issn><issn>1471-2393</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdks1u1DAUhSMEoqXwAiyQJTYsCNjxT5IVglFpK1WABKytO871jEcZO9jOVDwPL4rbGaopC8vWucefrq9PVb1k9B1jnXqfWNN1oqZNWaplolaPqlMmWlY3vOePj84n1bOUNpSytpP0aXXCe9pKwehp9ec7xjBF3MGI3iAJlqxxguyyS-QT2bk4JwJ-OFIXB9V5iya74Alsg1-RQll58JnchC0WMWf0gyuFoqGHDCMxELEUyMW8hhHIt-i2EH-Ty5AmV-pvyZcQ8_oGU8boyXleuzA5eF49sTAmfHHYz6qfn89_LC7r668XV4uP17URQua6bVAw09NhyYCCNT1YpawyjexA9INpLQczWCXl0KPBZugGxm3fcbpUSoLlZ9XVnjsE2Ohp35wO4PSdEOJKQ8zOjKhbaYeO28ZIy0VnC34pWtmCLJ0YA31hfdizpnm5xcGgzxHGB9CHFe_WehV2mpVPlZKzQnhzIMTway4j0VuXDI4jeAxz0px2iirWClWsr_-zbsIcfZlVcfWs6ZlitLiavcvEkFJEe98No_o2UHofKF0Cpe8CpW_Rr47fcX_lX4L4X_7Vy0U</recordid><startdate>20240729</startdate><enddate>20240729</enddate><creator>Belete, Debaka</creator><creator>Fekadie, Engidayehu</creator><creator>Kassaw, Melkamu</creator><creator>Fenta, Melaku</creator><creator>Jegnie, Azanu</creator><creator>Mulu, Tigist</creator><creator>Adane, Gashaw</creator><creator>Abebe, Wondwossen</creator><creator>Amare, Azanaw</creator><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240729</creationdate><title>Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia</title><author>Belete, Debaka ; Fekadie, Engidayehu ; Kassaw, Melkamu ; Fenta, Melaku ; Jegnie, Azanu ; Mulu, Tigist ; Adane, Gashaw ; Abebe, Wondwossen ; Amare, Azanaw</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-72e41c90db1a0afc9af66f6c258a49dc7f3acdf655d9ece2d8d13f9830b665af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Antigens</topic><topic>Blood & organ donations</topic><topic>Data collection</topic><topic>Ethiopia</topic><topic>Ethiopia - epidemiology</topic><topic>Female</topic><topic>Guhala</topic><topic>Hepacivirus - immunology</topic><topic>Hepatitis B</topic><topic>Hepatitis B - blood</topic><topic>Hepatitis B - epidemiology</topic><topic>Hepatitis B - transmission</topic><topic>Hepatitis B Surface Antigens - blood</topic><topic>Hepatitis B virus</topic><topic>Hepatitis B virus - immunology</topic><topic>Hepatitis C</topic><topic>Hepatitis C - blood</topic><topic>Hepatitis C - epidemiology</topic><topic>Hepatitis C - transmission</topic><topic>Hepatitis C Antibodies - blood</topic><topic>Hepatitis C virus</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious Disease Transmission, Vertical - statistics & numerical data</topic><topic>Laboratories</topic><topic>Liver cancer</topic><topic>Liver cirrhosis</topic><topic>Medical personnel</topic><topic>Mothers</topic><topic>Population</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - blood</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Pregnancy Complications, Infectious - virology</topic><topic>Pregnant women</topic><topic>Prenatal Care</topic><topic>Prevalence</topic><topic>Public health</topic><topic>Retrospective Studies</topic><topic>Seroepidemiologic Studies</topic><topic>Serology</topic><topic>Womens health</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Belete, Debaka</creatorcontrib><creatorcontrib>Fekadie, Engidayehu</creatorcontrib><creatorcontrib>Kassaw, Melkamu</creatorcontrib><creatorcontrib>Fenta, Melaku</creatorcontrib><creatorcontrib>Jegnie, Azanu</creatorcontrib><creatorcontrib>Mulu, Tigist</creatorcontrib><creatorcontrib>Adane, Gashaw</creatorcontrib><creatorcontrib>Abebe, Wondwossen</creatorcontrib><creatorcontrib>Amare, Azanaw</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals(OpenAccess)</collection><jtitle>BMC pregnancy and childbirth</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Belete, Debaka</au><au>Fekadie, Engidayehu</au><au>Kassaw, Melkamu</au><au>Fenta, Melaku</au><au>Jegnie, Azanu</au><au>Mulu, Tigist</au><au>Adane, Gashaw</au><au>Abebe, Wondwossen</au><au>Amare, Azanaw</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia</atitle><jtitle>BMC pregnancy and childbirth</jtitle><addtitle>BMC Pregnancy Childbirth</addtitle><date>2024-07-29</date><risdate>2024</risdate><volume>24</volume><issue>1</issue><spage>512</spage><epage>7</epage><pages>512-7</pages><artnum>512</artnum><issn>1471-2393</issn><eissn>1471-2393</eissn><abstract>Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia.
A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software.
In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women.
In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration.</abstract><cop>England</cop><pub>BioMed Central</pub><pmid>39075410</pmid><doi>10.1186/s12884-024-06714-6</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Age Antigens Blood & organ donations Data collection Ethiopia Ethiopia - epidemiology Female Guhala Hepacivirus - immunology Hepatitis B Hepatitis B - blood Hepatitis B - epidemiology Hepatitis B - transmission Hepatitis B Surface Antigens - blood Hepatitis B virus Hepatitis B virus - immunology Hepatitis C Hepatitis C - blood Hepatitis C - epidemiology Hepatitis C - transmission Hepatitis C Antibodies - blood Hepatitis C virus Hospitals Humans Infections Infectious Disease Transmission, Vertical - statistics & numerical data Laboratories Liver cancer Liver cirrhosis Medical personnel Mothers Population Pregnancy Pregnancy Complications, Infectious - blood Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - virology Pregnant women Prenatal Care Prevalence Public health Retrospective Studies Seroepidemiologic Studies Serology Womens health Young Adult |
title | Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia |
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