Scedosporium apiospermum fungemia successfully treated with voriconazole and terbinafine

Scedosporium apiospermum is ubiquitous in the environment and is considered an emerging infection. Immunocompromised hosts can have a wide spectrum of diseases ranging from cutaneous to disseminated disease that may involve pulmonary, central nervous system, or bone. Disseminated disease in immunoco...

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Bibliographic Details
Published in:IDCases 2020-01, Vol.22, p.e00928, Article e00928
Main Authors: Jabr, Ra’ed, Hammoud, Kassem
Format: Article
Language:English
Subjects:
Fungemia
Scedosporium apiospermum
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Summary:Scedosporium apiospermum is ubiquitous in the environment and is considered an emerging infection. Immunocompromised hosts can have a wide spectrum of diseases ranging from cutaneous to disseminated disease that may involve pulmonary, central nervous system, or bone. Disseminated disease in immunocompetent hosts is uncommon. Treatment of deep-seated infections is challenging because of the limited susceptibility of the Scedosporium species to all current antifungal drugs. We report a case of Scedosporidium apiospermum fungemia with a presumed pulmonary involvement in an immunocompetent patient. The fungemia was successfully treated with oral voriconazole and terbinafine.
ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2020.e00928