Protein-carbohydrate interactions as part of plant defense and animal immunity

The immune system consists of a complex network of cells and molecules that interact with each other to initiate the host defense system. Many of these interactions involve specific carbohydrate structures and proteins that specifically recognize and bind them, in particular lectins. It is well esta...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2015-05, Vol.20 (5), p.9029-9053
Main Authors: De Schutter, Kristof, Van Damme, Els J M
Format: Article
Language:English
Subjects:
animal immunity
carbohydrate
Carbohydrates - immunology
Immunity, Innate - immunology
lectin
Lectins - chemistry
plant defense
Plant Immunity - immunology
Proteins - immunology
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Summary:The immune system consists of a complex network of cells and molecules that interact with each other to initiate the host defense system. Many of these interactions involve specific carbohydrate structures and proteins that specifically recognize and bind them, in particular lectins. It is well established that lectin-carbohydrate interactions play a major role in the immune system, in that they mediate and regulate several interactions that are part of the immune response. Despite obvious differences between the immune system in animals and plants, there are also striking similarities. In both cases, lectins can play a role as pattern recognition receptors, recognizing the pathogens and initiating the stress response. Although plants do not possess an adaptive immune system, they are able to imprint a stress memory, a mechanism in which lectins can be involved. This review will focus on the role of lectins in the immune system of animals and plants.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules20059029