Reactivity of anti-gp43 antibodies from Paracoccidioides brasiliensis antiserum with extracts from cutaneous lesions of Lobo's disease. Preliminary note

We demonstrated through several immunochemical tests the presence of gp43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease. This glicoprotein is one of the immunodominant antigens in this species, and is used to identify it. The demonstration of gp43 tissues infec...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo 1997-01, Vol.39 (1), p.35-38
Main Authors: Vidal, M S, Palacios, S A, de Melo, N T, Lacaz, C da S
Format: Article
Language:English
Subjects:
Anti-GP-43 Antibodies
Antibodies, Anti-Idiotypic
Antigen-Antibody Reactions
Antigens, Fungal - immunology
Antigens, Surface
Fungal Proteins
Glycoproteins - immunology
Humans
Lobo's disease
Membrane Glycoproteins
Oligosaccharides - immunology
Paracoccidioides - immunology
Paracoccidioides brasiliensis
Paracoccidioidomycosis - diagnosis
Paracoccidioidomycosis - immunology
TROPICAL MEDICINE
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Summary:We demonstrated through several immunochemical tests the presence of gp43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease. This glicoprotein is one of the immunodominant antigens in this species, and is used to identify it. The demonstration of gp43 tissues infected by the agent of Jorge Lobo's disease is an additional evidence for classifying it in the genera Paracoccidioides, species loboi.
ISSN:0036-4665
1678-9946
0036-4665
1678-9946
DOI:10.1590/s0036-46651997000100007