PRIMARY HODGKIN'S LYMPHOMA OF THE BREAST INITIALLY TREATED BY SURGICAL EXCISION AND AXILLARY DISSECTION

Primary breast lymphoma accounts for 0.04%-0.5% of all breast malignancies. Primary non-Hodgkin's lymphomas of the breast are extremely rare and represent approximately 0.38%-0.7% of all cases. Epstein-Barr virus (EBV) has been postulated to play an important role in the pathogenesis of Hodgkin...

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Bibliographic Details
Published in:Acta clinica Croatica (Tisak) 2020-06, Vol.59 (2), p.365-367
Main Authors: Marton, Ingrid, Hrgović, Zlatko, Habek, Dubravko
Format: Article
Language:English
Subjects:
Aged
Breast Neoplasms - diagnosis
Breast Neoplasms - surgery
Breast Neoplasms - virology
Case Reports
Dissection
Epstein-Barr virus
Female
Herpesvirus 4, Human
Hodgkin Disease - diagnosis
Hodgkin Disease - surgery
Hodgkin Disease - virology
Hodgkin’s lymphoma
Humans
Immunohistochemistry
Primary breast lymphoma
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Summary:Primary breast lymphoma accounts for 0.04%-0.5% of all breast malignancies. Primary non-Hodgkin's lymphomas of the breast are extremely rare and represent approximately 0.38%-0.7% of all cases. Epstein-Barr virus (EBV) has been postulated to play an important role in the pathogenesis of Hodgkin's lymphoma. We present a case of EBV-positive primary Hodgkin's lymphoma of the breast. Although there is no sufficient data on this challenging diagnosis, it is known that it could be misdiagnosed with inflammatory breast carcinoma. A crucial part of the proper histopathologic diagnosis is immunohistochemistry. Different modalities of treatment include operative procedure, chemotherapy and radiotherapy. Recent studies suggest chemotherapy and radiotherapy to be initial treatment for patients with primary breast lymphomas.
ISSN:0353-9466
1333-9451
DOI:10.20471/acc.2020.59.02.22