Worsening cytology and lesion enlargement are useful indicators for malignant transformation of lobular endocervical glandular hyperplasia during follow-up: A case report

•We report a case of MDA arising from clinical LEGH during 5 years of follow-up.•The first sign suggesting MDA was cellular atypia in endocervical cytology, and was followed by an increase in tumor size.•MDA lesion lacked in stromal reaction and MRI failed to detected MDA.•Worsening cytology and les...

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Bibliographic Details
Published in:Gynecologic oncology reports 2020-05, Vol.32, p.100571, Article 100571
Main Authors: Kobara, Hisanori, Miyamoto, Tsutomu, Otsuki, Toshiaki, Ohya, Ayumi, Shiozawa, Tanri
Format: Article
Language:English
Subjects:
Case Report
Gastric-type mucin
Lobular endocervical glandular hyperplasia
Magnetic resonance imaging
Malignant transformation
Minimal deviation adenocarcinoma
Papanicolaou cytology
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Summary:•We report a case of MDA arising from clinical LEGH during 5 years of follow-up.•The first sign suggesting MDA was cellular atypia in endocervical cytology, and was followed by an increase in tumor size.•MDA lesion lacked in stromal reaction and MRI failed to detected MDA.•Worsening cytology and lesion enlargement are important signs for malignant change of LEGH during follow-up.
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2020.100571