Impact of PM2.5, relative humidity, and temperature on sleep quality: a cross-sectional study in Taipei

• Published in: Annals of medicine (Helsinki) 2025-12, Vol.57 (1), p.2448733
• Main Authors: Thanh Tung, Nguyen, Lee, Yueh-Lun, Liu, Wen-Te, Lin, Yuan-Chien, Chang, Jer-Hwa, Xuan Thao, Huynh Nguyen, Ba Dung, Hoang, Viet Trung, Lam, Phan Chung Thuy, Tran, Thi Hien, Nguyen, Tsai, Cheng-Yu, Lo, Chen-Chen, Lo, Kang, Ho, Kin Fai, Chuang, Kai-Jen, Chuang, Hsiao-Chi
• Format: Article
• Language: English
• Subjects: Air pollution; climate change; obstructive sleep apnea; relative humidity; temperature
• ISSN: 1365-2060; 0785-3890; 1365-2060
• DOI: 10.1080/07853890.2024.2448733

TWe investigated impacts of particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5), relative humidity (RH), and temperature on sleep stages and arousal.INTRODUCTIONTWe investigated impacts of particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5), relative humidity (RH), and temperature on sleep stages and arousal.A cross-sectional analysis involving 8,611 participants was conducted at a sleep center in Taipei. We estimated individual-level exposure to RH, temperature, and PM2.5 over 1-day, 7-day, and 30-day periods. Linear regression models assessed the relationship between these environmental factors and sleep parameters across different seasons. Mediation analysis was used to explore PM2.5, RH, and temperature roles in these relationships.MATERIALS AND METHODSA cross-sectional analysis involving 8,611 participants was conducted at a sleep center in Taipei. We estimated individual-level exposure to RH, temperature, and PM2.5 over 1-day, 7-day, and 30-day periods. Linear regression models assessed the relationship between these environmental factors and sleep parameters across different seasons. Mediation analysis was used to explore PM2.5, RH, and temperature roles in these relationships.A 1% increase in RH over 1 and 7 days was associated with changes in non-rapid eye movement (NREM) sleep stages and increases in the arousal index across all seasons. A 1°C increase in temperature over similar periods led to increases in rapid eye movement (REM) sleep. During cold season, changes in RH and temperature were linked to variations in arousal and NREM sleep stages. In hot season, RH and temperature increases were correlated with changes in NREM sleep stages and arousal. Across all groups, a 1-μg/m³ increase in PM2.5 levels was associated with alterations in NREM and REM sleep stages and increases in the arousal index. We found PM2.5 levels mediated relationships between RH, temperature, and various sleep stages, particularly in cold season.RESULTSA 1% increase in RH over 1 and 7 days was associated with changes in non-rapid eye movement (NREM) sleep stages and increases in the arousal index across all seasons. A 1°C increase in temperature over similar periods led to increases in rapid eye movement (REM) sleep. During cold season, changes in RH and temperature were linked to variations in arousal and NREM sleep stages. In hot season, RH and temperature increases were correlated with changes in NREM sleep stages and ar