Purification and Identification of Novel Xanthine Oxidase Inhibitory Peptides Derived from Round Scad ( Decapterus maruadsi ) Protein Hydrolysates

The objective of the present study was to investigate the xanthine oxidase (XO) inhibitory effects of peptides purified and identified from round scad ( ) hydrolysates (RSHs). In this study, RSHs were obtained by using three proteases (neutrase, protamex and alcalase). Among them, the RSHs of 6-h hy...

Full description

Saved in:
Bibliographic Details
Published in:Marine drugs 2021-09, Vol.19 (10), p.538
Main Authors: Hu, Xiao, Zhou, Ya, Zhou, Shaobo, Chen, Shengjun, Wu, Yanyan, Li, Laihao, Yang, Xianqing
Format: Article
Language:English
Subjects:
Affinity chromatography
Amino acid sequences
Amino acids
Animals
Aquatic Organisms
Chromatography
Chromatography, High Pressure Liquid
Decapterus maruadsi
Disease
DNA
Enzyme Inhibitors - chemistry
Enzymes
Fish Proteins - chemistry
Fishes
Fluorescence
High performance liquid chromatography
HPLC
Hydrolysates
hydrolysis
Hypertension
Identification
Kinetics
Liquid chromatography
Marine fishes
Mass spectrometry
Mass spectroscopy
Metals
Molecular docking
Molecular Docking Simulation
Peptides
Protein Hydrolysates - chemistry
Protein purification
Proteins
purification
Quenching
Rheumatism
round scad (Decapterus maruadsi)
Subtilisin
Uric acid
Water purification
Xanthine oxidase
Xanthine Oxidase - antagonists & inhibitors
xanthine oxidase inhibitory
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of the present study was to investigate the xanthine oxidase (XO) inhibitory effects of peptides purified and identified from round scad ( ) hydrolysates (RSHs). In this study, RSHs were obtained by using three proteases (neutrase, protamex and alcalase). Among them, the RSHs of 6-h hydrolysis by neutrase displayed the strongest XO inhibitory activity and had an abundance of small peptides (
ISSN:1660-3397
1660-3397
DOI:10.3390/md19100538