Live Cell Therapy as Potential Risk Factor for Q Fever

During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the Un...

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Bibliographic Details
Published in:Emerging infectious diseases 2017-07, Vol.23 (7), p.1210-1212
Main Authors: George, Maja, Reich, Andreas, Cussler, Klaus, Jehl, Herrmann, Burckhardt, Florian
Format: Article
Language:English
Subjects:
Adult
Animals
bacteria
Cell- and Tissue-Based Therapy - adverse effects
Coxiella burnetii
Coxiella burnetii - immunology
Disease Outbreaks
Female
Germany - epidemiology
Health aspects
Humans
live cell therapy
Live Cell Therapy as Potential Risk Factor for Q Fever
Livestock
Male
Middle Aged
outbreaks
Q fever
Q Fever - diagnosis
Q Fever - epidemiology
Q Fever - etiology
Research Letter
risk factor
Risk Factors
Sheep
Sheep Diseases - microbiology
Zoonoses
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Description
Summary:During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the United States.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2307.161693