SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin

Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deep...

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Bibliographic Details
Published in:Animals (Basel) 2023-01, Vol.13 (2), p.193
Main Authors: Cerezo, Isabel M, Pérez-Gómez, Olivia, Bautista, Rocio, Seoane, Pedro, Esteban, M Ángeles, Balebona, M Carmen, Moriñigo, Miguel A, Tapia-Paniagua, Silvana T
Format: Article
Language:English
Subjects:
Achromobacter
Aquaculture
Aquariums
Biofilms
Biopsy
Cell differentiation
Cell proliferation
Correlation
Diet
fish
Fish farms
Fish skins
Gene silencing
Genes
gilthead seabream
Inflammation
Microbiota
Pathogens
probiotic
Probiotics
RNA seq
Skin
Skin diseases
Skin lesions
Transcriptomics
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Summary:Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of , and related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms ( ), cell migration and differentiation ( , , , ); and repression of genes related to cell proliferation ( , ), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, , f_ , p_ , and genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies.
ISSN:2076-2615
2076-2615
DOI:10.3390/ani13020193