Evaluation of sleep profile in schizophrenia patients treated with extended-release paliperidone: an open-label prospective study in Southeast Asia

To evaluate the effect of 6 months of treatment with paliperidone extended-release (ER) tablets on the sleep profile of patients with schizophrenia. A total of 984 patients meeting the (DSM-IV) criteria for schizophrenia who switched their antipsychotic to paliperidone ER were recruited from 61 site...

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Bibliographic Details
Published in:Psychology research and behavior management 2017-01, Vol.10, p.323-327
Main Authors: Kongsakon, Ronnachai, Thavichachart, Nuntika, Chung, Ka Fai, Lim, Leslie, Azucena, Beverly, Rondain, Elizabeth, Go, Benson, Costales, Fe, Nerapusee, Osot
Format: Article
Language:English
Subjects:
Analysis
Antipsychotics
Dosage and administration
Drug dosages
Drug therapy
Ethics
Health aspects
Hospitals
Original Research
Paliperidone
Paliperidone ER
Patient satisfaction
Population
Psychiatry
Psychotropic drugs
Quality
Risk factors
Schizophrenia
Sleep
Sleep profile
Statistical analysis
Systematic review
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Description
Summary:To evaluate the effect of 6 months of treatment with paliperidone extended-release (ER) tablets on the sleep profile of patients with schizophrenia. A total of 984 patients meeting the (DSM-IV) criteria for schizophrenia who switched their antipsychotic to paliperidone ER were recruited from 61 sites in five countries in Southeast Asia. We recorded patient demographics and assessed sleep quality and daytime drowsiness using visual analog scales. Approximately 70% of patients completed the 6-month study. After the use of paliperidone ER, patients reported significantly better sleep quality (76.44 vs 65.48;
ISSN:1179-1578
1179-1578
DOI:10.2147/PRBM.S132272