Update on Pediatric Sepsis in Mexico

The main objective of this work was to determine and update the causal agents’ antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosi...

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Bibliographic Details
Published in:Global pediatric health 2022, Vol.9, p.2333794X221118017-2333794X221118017
Main Authors: Donath Benitez, Crisell Arely, Mattenberger-Cantú, Estefanía, Salas-Flores, Ricardo, Gómez-Morales, Guillermo Baudelio, Mártinez-Diaz, Paola Alejandra, Moreno-Treviño, María Guadalupe, García-Tovar, Laura Elvira, González-Salazar, Francisco
Format: Article
Language:English
Subjects:
Antibiotics
Blood
Microorganisms
Pediatrics
Section: Infectious Diseases
Sepsis
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Summary:The main objective of this work was to determine and update the causal agents’ antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosis of sepsis were reviewed according to the SOFA criteria during 2020 in a public hospital in Mexico. A total of 207 blood cultures were performed and analyzed. The main isolated microorganisms were Staphylococcus, followed by Klebsiella and Escherichia. Several microorganisms showed 100% of sensitivity to different antibiotics or antifungals, some of them include Vancomycin, Voriconazole, Meropenem, Ciprofloxacin, and Cefotaxime. Bacteria of genre Staphylococcus showed its highest sensitivity rate to Tigecycline with 63.3%. Too Staphylococcus showed the highest resistance rate to Oxacillin with 50%. Although the patterns of sepsis-causing germs are similar to those previously reported, the development of new drugs with greater efficacy is the main contribution.
ISSN:2333-794X
2333-794X
DOI:10.1177/2333794X221118017