Effect of astaxanthin and fish oil on enzymatic antioxidant system and α-amylase activity of salivary glands from rats

Salivary glands contribute to oral health. It is therefore of interest to study therapies that may favor their function and protection. Aim: To evaluate the effect of astaxanthin, fish oil and association of them on enzymatic antioxidant system and functional parameters of salivary glands. Methods:...

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Bibliographic Details
Published in:Brazilian journal of oral sciences 2015-10, Vol.13 (1)
Main Authors: Mariana Ferreira Leite, Amanda Martins de Lima, Simone Jee Sun Kang, Maria Teresa Botti Rodrigues dos Santos, Rosemari Otton
Format: Article
Language:English
Subjects:
Antioxidant system
Astaxanthin
Fish oil
Salivary glands
α-amylase
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Summary:Salivary glands contribute to oral health. It is therefore of interest to study therapies that may favor their function and protection. Aim: To evaluate the effect of astaxanthin, fish oil and association of them on enzymatic antioxidant system and functional parameters of salivary glands. Methods: Healthy rats (n=32) were divided into 4 groups: untreated-control, astaxanthin-treated (1 mg/kg body weight- BW), fish oil-treated (10 mg EPA/kg BW and 7 mg DHA/kg BW), and fish oil plus astaxanthin-treated. A prophylactic dose was administered in each group daily by gavage, for 45 days. Superoxide dismutase (SOD), catalase, glutathione peroxidase, reductase, and α-amylase activities were determined in salivary glands and compared by ANOVA and Tukey post-test (p
ISSN:1677-3225
DOI:10.20396/bjos.v13i1.8640934