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Period of hospitalization and mortality in transferred versus non-transferred COVID-19 patients: results from Germany
COVID-19 was a challenge for health-care systems worldwide, causing large numbers of hospitalizations and inter-hospital transfers. We studied whether transfer, as well as its reason, was associated with the duration of hospitalization in non-ICU and ICU patients. For this purpose, all patients hosp...
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Published in: | Scientific reports 2024-03, Vol.14 (1), p.7338-7338, Article 7338 |
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description | COVID-19 was a challenge for health-care systems worldwide, causing large numbers of hospitalizations and inter-hospital transfers. We studied whether transfer, as well as its reason, was associated with the duration of hospitalization in non-ICU and ICU patients. For this purpose, all patients hospitalized due to COVID-19 between August 1st and December 31st, 2021, in a network of hospitals in Southern Germany were comprehensively characterized regarding their clinical course, therapy, complications, transfers, reasons for transfer, involved levels of care, total period of hospitalization and in-hospital mortality, using univariate and multiple regression analyses. While mortality was not significantly associated with transfer, the period of hospitalization was. In non-ICU patients (
n
= 545), median (quartiles) time was 7.0 (4.0–11.0) in non-transferred (
n
= 458) and 18.0 (11.0–29.0) days in transferred (
n
= 87) patients (
p
|
doi_str_mv | 10.1038/s41598-024-57272-y |
format | article |
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n
= 545), median (quartiles) time was 7.0 (4.0–11.0) in non-transferred (
n
= 458) and 18.0 (11.0–29.0) days in transferred (
n
= 87) patients (
p
< 0.001). In ICU patients (
n
= 100 transferred,
n
= 115 non-transferred) it was 12.0 (8.3–18.0) and 22.0 (15.0–34.0) days (
p
< 0.001). Beyond ECMO therapy (4.5%), reasons for transfer were medical (33.2%) or capacity (61.9%) reasons, with medical/capacity reasons in 32/49 of non-ICU and 21/74 of ICU patients. Thus, the transfer of COVID-19 patients between hospitals was associated with longer periods of hospitalization, corresponding to greater health care utilization, for which specific patient characteristics and clinical decisions played a role.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-024-57272-y</identifier><identifier>PMID: 38538711</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699/255/2514 ; 692/700/228 ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - therapy ; Health care ; Hospital Mortality ; Hospitalization ; Hospitals ; Humanities and Social Sciences ; Humans ; Intensive Care Units ; Mortality ; multidisciplinary ; Patient Transfer ; Patients ; Regression Analysis ; Retrospective Studies ; Science ; Science (multidisciplinary)</subject><ispartof>Scientific reports, 2024-03, Vol.14 (1), p.7338-7338, Article 7338</ispartof><rights>The Author(s) 2024</rights><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c492t-3690389c52ff5cadd60512c1c552ca0677e4bcf915fd0c954f6e6f43f89fe3dc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3003351589/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3003351589?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,74998</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38538711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Suski, Pascal</creatorcontrib><creatorcontrib>Jörres, Rudolf A.</creatorcontrib><creatorcontrib>Engelhardt, Sebastian</creatorcontrib><creatorcontrib>Kahnert, Kathrin</creatorcontrib><creatorcontrib>Lenherr, Katharina</creatorcontrib><creatorcontrib>Bauer, Andreas</creatorcontrib><creatorcontrib>Budweiser, Stephan</creatorcontrib><title>Period of hospitalization and mortality in transferred versus non-transferred COVID-19 patients: results from Germany</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>COVID-19 was a challenge for health-care systems worldwide, causing large numbers of hospitalizations and inter-hospital transfers. We studied whether transfer, as well as its reason, was associated with the duration of hospitalization in non-ICU and ICU patients. For this purpose, all patients hospitalized due to COVID-19 between August 1st and December 31st, 2021, in a network of hospitals in Southern Germany were comprehensively characterized regarding their clinical course, therapy, complications, transfers, reasons for transfer, involved levels of care, total period of hospitalization and in-hospital mortality, using univariate and multiple regression analyses. While mortality was not significantly associated with transfer, the period of hospitalization was. In non-ICU patients (
n
= 545), median (quartiles) time was 7.0 (4.0–11.0) in non-transferred (
n
= 458) and 18.0 (11.0–29.0) days in transferred (
n
= 87) patients (
p
< 0.001). In ICU patients (
n
= 100 transferred,
n
= 115 non-transferred) it was 12.0 (8.3–18.0) and 22.0 (15.0–34.0) days (
p
< 0.001). Beyond ECMO therapy (4.5%), reasons for transfer were medical (33.2%) or capacity (61.9%) reasons, with medical/capacity reasons in 32/49 of non-ICU and 21/74 of ICU patients. Thus, the transfer of COVID-19 patients between hospitals was associated with longer periods of hospitalization, corresponding to greater health care utilization, for which specific patient characteristics and clinical decisions played a role.</description><subject>692/699/255/2514</subject><subject>692/700/228</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - therapy</subject><subject>Health care</subject><subject>Hospital Mortality</subject><subject>Hospitalization</subject><subject>Hospitals</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Intensive Care Units</subject><subject>Mortality</subject><subject>multidisciplinary</subject><subject>Patient Transfer</subject><subject>Patients</subject><subject>Regression Analysis</subject><subject>Retrospective Studies</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kk1v1DAQhiMEolXpH-CALHHhEvBnYnNBaAtlpUrlAFwtxxlvvUrsxU4qLb8eb1PKlgO-2Jp55_GM_VbVS4LfEszku8yJULLGlNeipS2t90-qU4q5qCmj9OnR-aQ6z3mLyxJUcaKeVydMCiZbQk6r-SskH3sUHbqJeecnM_hfZvIxIBN6NMZ0iEx75AOakgnZQUrQo1tIec4oxFAfh1fXP9YXNVFoVxgQpvweJcjzMGXkUhzRJaTRhP2L6pkzQ4bz-_2s-v7507fVl_rq-nK9-nhVW67oVLNGlVGVFdQ5YU3fN1gQaokVglqDm7YF3lmniHA9tkpw10DjOHNSOWC9ZWfVeuH20Wz1LvnRpL2Oxuu7QEwbbdLk7QC6lR1WnROiZ4xbxSS2ncAWJEgnWqYK68PC2s3dCL0t0yUzPII-zgR_ozfxVhOsWsapLIQ394QUf86QJz36bGEYTIA4Z80w4bj8WkOK9PU_0m2cUyhvVVSYMUGEPLREF5VNMecE7qEbgvXBJXpxiS4u0Xcu0ftS9Op4joeSP54oArYIckmFDaS_d_8H-xua9so9</recordid><startdate>20240328</startdate><enddate>20240328</enddate><creator>Suski, Pascal</creator><creator>Jörres, Rudolf A.</creator><creator>Engelhardt, Sebastian</creator><creator>Kahnert, Kathrin</creator><creator>Lenherr, Katharina</creator><creator>Bauer, Andreas</creator><creator>Budweiser, Stephan</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><general>Nature Portfolio</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240328</creationdate><title>Period of hospitalization and mortality in transferred versus non-transferred COVID-19 patients: results from Germany</title><author>Suski, Pascal ; 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We studied whether transfer, as well as its reason, was associated with the duration of hospitalization in non-ICU and ICU patients. For this purpose, all patients hospitalized due to COVID-19 between August 1st and December 31st, 2021, in a network of hospitals in Southern Germany were comprehensively characterized regarding their clinical course, therapy, complications, transfers, reasons for transfer, involved levels of care, total period of hospitalization and in-hospital mortality, using univariate and multiple regression analyses. While mortality was not significantly associated with transfer, the period of hospitalization was. In non-ICU patients (
n
= 545), median (quartiles) time was 7.0 (4.0–11.0) in non-transferred (
n
= 458) and 18.0 (11.0–29.0) days in transferred (
n
= 87) patients (
p
< 0.001). In ICU patients (
n
= 100 transferred,
n
= 115 non-transferred) it was 12.0 (8.3–18.0) and 22.0 (15.0–34.0) days (
p
< 0.001). Beyond ECMO therapy (4.5%), reasons for transfer were medical (33.2%) or capacity (61.9%) reasons, with medical/capacity reasons in 32/49 of non-ICU and 21/74 of ICU patients. Thus, the transfer of COVID-19 patients between hospitals was associated with longer periods of hospitalization, corresponding to greater health care utilization, for which specific patient characteristics and clinical decisions played a role.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>38538711</pmid><doi>10.1038/s41598-024-57272-y</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 692/699/255/2514 692/700/228 COVID-19 COVID-19 - epidemiology COVID-19 - therapy Health care Hospital Mortality Hospitalization Hospitals Humanities and Social Sciences Humans Intensive Care Units Mortality multidisciplinary Patient Transfer Patients Regression Analysis Retrospective Studies Science Science (multidisciplinary) |
title | Period of hospitalization and mortality in transferred versus non-transferred COVID-19 patients: results from Germany |
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