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Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis
Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in compa...
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Published in: | International journal of cardiology. Heart & vasculature 2022-08, Vol.41, p.101058, Article 101058 |
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container_title | International journal of cardiology. Heart & vasculature |
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creator | Pourasghari, Hamid Tavolinejad, Hamed Soleimanpour, Samira Abdi, Zhaleh Arabloo, Jalal Bragazzi, Nicola Luigi Behzadifar, Masoud Rashedi, Sina Omidi, Negar Ayoubian, Ali Tajdini, Masih Ghorashi, Seyyed Mojtaba Azari, Samad |
description | Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p |
doi_str_mv | 10.1016/j.ijcha.2022.101058 |
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In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p < 0.001; 28 studies). Patients hospitalized for STEMI and NSTEMI were 29% and 34% respectively less in the COVID-19 era compared with periods before COVID-19, which was statistically significantly (OR = 0.71; 95% CI: 0.65 –0.78; I2 = 93%; p < 0.001; 22 studies, OR = 0.66; 95% CI: 0.58–0.73; I2 = 95%; p < 0.001; 14 studies). The overall rate of in-hospital mortality in AMI patients increased by 26% in the COVID-19 era, which was not statistically significant (OR = 1.26; 95% CI: 1.0–1.59; I2 = 22%; p < 0.001; six studies). The rate of in-hospital mortality in STEMI and NSTEMI patients increased by 15% and 26% respectively in the COVID-19 era, which was not statistically significant (OR = 1.15; 95% CI: 0.85–1.57; I2 = 48%; p = 0.035; 11 studies, OR = 1.35; 95% CI: 0.64–2.86; I2 = 45%; p = 0.157; 3 articles). These observations highlight the challenges in the adaptation of health-care systems with the impact of the COVID-19 pandemic.</description><identifier>ISSN: 2352-9067</identifier><identifier>EISSN: 2352-9067</identifier><identifier>DOI: 10.1016/j.ijcha.2022.101058</identifier><identifier>PMID: 35647263</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Acute myocardial Infarction ; COVID-19 ; Meta-analysis ; Review ; SARS-CoV2 ; Systematic review</subject><ispartof>International journal of cardiology. Heart & vasculature, 2022-08, Vol.41, p.101058, Article 101058</ispartof><rights>2022 The Authors</rights><rights>2022 Published by Elsevier B.V.</rights><rights>2022 Published by Elsevier B.V. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-b11afe0420dcdef100f42ea692baa6433ee53d4b31870733da0fe90ef36609063</citedby><cites>FETCH-LOGICAL-c455t-b11afe0420dcdef100f42ea692baa6433ee53d4b31870733da0fe90ef36609063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124953/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S2352906722001075$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3549,27924,27925,45780,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35647263$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pourasghari, Hamid</creatorcontrib><creatorcontrib>Tavolinejad, Hamed</creatorcontrib><creatorcontrib>Soleimanpour, Samira</creatorcontrib><creatorcontrib>Abdi, Zhaleh</creatorcontrib><creatorcontrib>Arabloo, Jalal</creatorcontrib><creatorcontrib>Bragazzi, Nicola Luigi</creatorcontrib><creatorcontrib>Behzadifar, Masoud</creatorcontrib><creatorcontrib>Rashedi, Sina</creatorcontrib><creatorcontrib>Omidi, Negar</creatorcontrib><creatorcontrib>Ayoubian, Ali</creatorcontrib><creatorcontrib>Tajdini, Masih</creatorcontrib><creatorcontrib>Ghorashi, Seyyed Mojtaba</creatorcontrib><creatorcontrib>Azari, Samad</creatorcontrib><title>Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis</title><title>International journal of cardiology. Heart & vasculature</title><addtitle>Int J Cardiol Heart Vasc</addtitle><description>Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p < 0.001; 28 studies). Patients hospitalized for STEMI and NSTEMI were 29% and 34% respectively less in the COVID-19 era compared with periods before COVID-19, which was statistically significantly (OR = 0.71; 95% CI: 0.65 –0.78; I2 = 93%; p < 0.001; 22 studies, OR = 0.66; 95% CI: 0.58–0.73; I2 = 95%; p < 0.001; 14 studies). The overall rate of in-hospital mortality in AMI patients increased by 26% in the COVID-19 era, which was not statistically significant (OR = 1.26; 95% CI: 1.0–1.59; I2 = 22%; p < 0.001; six studies). The rate of in-hospital mortality in STEMI and NSTEMI patients increased by 15% and 26% respectively in the COVID-19 era, which was not statistically significant (OR = 1.15; 95% CI: 0.85–1.57; I2 = 48%; p = 0.035; 11 studies, OR = 1.35; 95% CI: 0.64–2.86; I2 = 45%; p = 0.157; 3 articles). 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Heart & vasculature</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pourasghari, Hamid</au><au>Tavolinejad, Hamed</au><au>Soleimanpour, Samira</au><au>Abdi, Zhaleh</au><au>Arabloo, Jalal</au><au>Bragazzi, Nicola Luigi</au><au>Behzadifar, Masoud</au><au>Rashedi, Sina</au><au>Omidi, Negar</au><au>Ayoubian, Ali</au><au>Tajdini, Masih</au><au>Ghorashi, Seyyed Mojtaba</au><au>Azari, Samad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis</atitle><jtitle>International journal of cardiology. Heart & vasculature</jtitle><addtitle>Int J Cardiol Heart Vasc</addtitle><date>2022-08-01</date><risdate>2022</risdate><volume>41</volume><spage>101058</spage><pages>101058-</pages><artnum>101058</artnum><issn>2352-9067</issn><eissn>2352-9067</eissn><abstract>Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p < 0.001; 28 studies). Patients hospitalized for STEMI and NSTEMI were 29% and 34% respectively less in the COVID-19 era compared with periods before COVID-19, which was statistically significantly (OR = 0.71; 95% CI: 0.65 –0.78; I2 = 93%; p < 0.001; 22 studies, OR = 0.66; 95% CI: 0.58–0.73; I2 = 95%; p < 0.001; 14 studies). The overall rate of in-hospital mortality in AMI patients increased by 26% in the COVID-19 era, which was not statistically significant (OR = 1.26; 95% CI: 1.0–1.59; I2 = 22%; p < 0.001; six studies). The rate of in-hospital mortality in STEMI and NSTEMI patients increased by 15% and 26% respectively in the COVID-19 era, which was not statistically significant (OR = 1.15; 95% CI: 0.85–1.57; I2 = 48%; p = 0.035; 11 studies, OR = 1.35; 95% CI: 0.64–2.86; I2 = 45%; p = 0.157; 3 articles). These observations highlight the challenges in the adaptation of health-care systems with the impact of the COVID-19 pandemic.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>35647263</pmid><doi>10.1016/j.ijcha.2022.101058</doi><oa>free_for_read</oa></addata></record> |
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subjects | Acute myocardial Infarction COVID-19 Meta-analysis Review SARS-CoV2 Systematic review |
title | Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis |
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