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Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis

Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in compa...

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Published in:International journal of cardiology. Heart & vasculature 2022-08, Vol.41, p.101058, Article 101058
Main Authors: Pourasghari, Hamid, Tavolinejad, Hamed, Soleimanpour, Samira, Abdi, Zhaleh, Arabloo, Jalal, Bragazzi, Nicola Luigi, Behzadifar, Masoud, Rashedi, Sina, Omidi, Negar, Ayoubian, Ali, Tajdini, Masih, Ghorashi, Seyyed Mojtaba, Azari, Samad
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container_title International journal of cardiology. Heart & vasculature
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creator Pourasghari, Hamid
Tavolinejad, Hamed
Soleimanpour, Samira
Abdi, Zhaleh
Arabloo, Jalal
Bragazzi, Nicola Luigi
Behzadifar, Masoud
Rashedi, Sina
Omidi, Negar
Ayoubian, Ali
Tajdini, Masih
Ghorashi, Seyyed Mojtaba
Azari, Samad
description Since the SARS-CoV-2 pandemic began, numerous studies have reported a concerning drop in the number of acute myocardial infarction (AMI) admissions. In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p 
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In the present systematic review and meta-analysis, we aimed to compare the rate of AMI admissions and major complication during the pandemic, in comparison with pre-pandemic periods. Three major databases (PubMed, Scopus, and Web of Science Core Collection) were searched. Out of 314 articles, 41 were entered into the study. Patients hospitalized for AMI were 35% less in the COVID-19 era compared with pre-pandemic periods, which was statistically significantly (OR = 0.65; 95% CI: 0.56–0.74; I2 = 99%; p &lt; 0.001; 28 studies). Patients hospitalized for STEMI and NSTEMI were 29% and 34% respectively less in the COVID-19 era compared with periods before COVID-19, which was statistically significantly (OR = 0.71; 95% CI: 0.65 –0.78; I2 = 93%; p &lt; 0.001; 22 studies, OR = 0.66; 95% CI: 0.58–0.73; I2 = 95%; p &lt; 0.001; 14 studies). The overall rate of in-hospital mortality in AMI patients increased by 26% in the COVID-19 era, which was not statistically significant (OR = 1.26; 95% CI: 1.0–1.59; I2 = 22%; p &lt; 0.001; six studies). The rate of in-hospital mortality in STEMI and NSTEMI patients increased by 15% and 26% respectively in the COVID-19 era, which was not statistically significant (OR = 1.15; 95% CI: 0.85–1.57; I2 = 48%; p = 0.035; 11 studies, OR = 1.35; 95% CI: 0.64–2.86; I2 = 45%; p = 0.157; 3 articles). 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source ScienceDirect Journals; PubMed Central
subjects Acute myocardial Infarction
COVID-19
Meta-analysis
Review
SARS-CoV2
Systematic review
title Hospitalization, major complications and mortality in acute myocardial infarction patients during the COVID-19 era: A systematic review and meta-analysis
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