Meconium Aspiration Syndrome: A Narrative Review

Meconium aspiration syndrome is a clinical condition characterized by respiratory failure occurring in neonates born through meconium-stained amniotic fluid. Worldwide, the incidence has declined in developed countries thanks to improved obstetric practices and perinatal care while challenges persis...

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Bibliographic Details
Published in:Children (Basel) 2021-03, Vol.8 (3), p.230
Main Authors: Monfredini, Chiara, Cavallin, Francesco, Villani, Paolo Ernesto, Paterlini, Giuseppe, Allais, Benedetta, Trevisanuto, Daniele
Format: Article
Language:English
Subjects:
Acidosis
Airway management
Amniotic fluid
Childrens health
Feces
Fetuses
HIV
Human immunodeficiency virus
Hypoxia
infant newborn
Infections
Inflammation
Intubation
meconium aspiration syndrome
meconium-stained amniotic fluid
Newborn babies
Pathophysiology
Pediatrics
Pulmonary hypertension
Respiratory failure
Review
Risk factors
Surfactants
Umbilical cord
Ventilators
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Summary:Meconium aspiration syndrome is a clinical condition characterized by respiratory failure occurring in neonates born through meconium-stained amniotic fluid. Worldwide, the incidence has declined in developed countries thanks to improved obstetric practices and perinatal care while challenges persist in developing countries. Despite the improved survival rate over the last decades, long-term morbidity among survivors remains a major concern. Since the 1960s, relevant changes have occurred in the perinatal and postnatal management of such patients but the most appropriate approach is still a matter of debate. This review offers an updated overview of the epidemiology, etiopathogenesis, diagnosis, management and prognosis of infants with meconium aspiration syndrome.
ISSN:2227-9067
2227-9067
DOI:10.3390/children8030230