Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Abstract Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation:...

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Published in:Case reports in oncology 2024-03, Vol.17 (1), p.477-483
Main Authors: Zrinšćak, Ognjen, Kasumović, Armin, Krolo, Iva, Ivekovic, Renata, Malenica Ravlić, Maja, Tomašković, Igor, Vatavuk, Zoran
Format: Article
Language:English
Subjects:
Abdomen
Biomarkers
Cancer therapies
Case Report
Case reports
Eye cancer
eye metastasis
eyelid tumor
Immunotherapy
Kidney cancer
Kinases
Metastasis
Patients
renal carcinoma
Tumors
Ultrasonic imaging
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Summary:Abstract Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient. Conclusion: The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients.
ISSN:1662-6575
1662-6575
DOI:10.1159/000537860