Causes of Death in Long-Term Nasopharyngeal Carcinoma Survivors

PurposeTo assess the causes of death (COD) and long-term survival after nasopharyngeal carcinoma (NPC) diagnosis. MethodsUsing linked data from the Surveillance, Epidemiology, and End Results program, patients with NPC diagnosed from 1990 to 2010 and followed up >5 years were identified. Chi-squa...

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Bibliographic Details
Published in:Frontiers in public health 2022-07, Vol.10, p.912843-912843
Main Authors: Yang, Shi-Ping, Rao, Ming-Yue, Chen, Qing-Shuang, Zhou, Ping, Lian, Chen-Lu, Wu, San-Gang
Format: Article
Language:English
Subjects:
cause of death
long-term survival
nasopharyngeal carcinoma
Public Health
SEER
survivors
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Summary:PurposeTo assess the causes of death (COD) and long-term survival after nasopharyngeal carcinoma (NPC) diagnosis. MethodsUsing linked data from the Surveillance, Epidemiology, and End Results program, patients with NPC diagnosed from 1990 to 2010 and followed up >5 years were identified. Chi-squared test, the Kaplan-Meier method, and the Cox proportional hazard model were used for analyses. ResultsAmong the 3,036 long-term NPC survivors, 1,432 survived for >5-10 years and 1,604 survived for >10 years. The most common COD was primary NPC (36.9%), followed by other causes (28.7%), other cancers (15.3%), cardiac disease (12.9%), and non-malignant pulmonary disease (6.2%). With a median follow-up of 125 months, deaths from NPC decreased with increasing time from diagnosis, while death because of cardiac disease and other causes increased. In those aged
ISSN:2296-2565
2296-2565
DOI:10.3389/fpubh.2022.912843