Patient-ventilator asynchrony as a predictor of weaning failure in mechanically ventilated COPD patients

Background Patient-ventilator asynchrony is a common problem in mechanically ventilated patients. It is associated with adverse effects including increased work of breathing, patient discomfort, increased need for sedation, prolonged mechanical ventilation, weaning difficulties, and weaning failure....

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Bibliographic Details
Published in:The Egyptian Journal of Bronchology 2021-12, Vol.15 (1), p.1-7, Article 30
Main Authors: Sadek, Samiaa H., El-kholy, Maha M., Abdulmoez, Marwa S., El-Morshedy, Reham M.
Format: Article
Language:English
Subjects:
Anesthesia
Asynchrony
Chronic obstructive pulmonary disease
COPD
Intubation
Mechanically ventilated
Medicine
Medicine & Public Health
Ostomy
Patients
Ventilators
Weaning
Weaning failure
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Summary:Background Patient-ventilator asynchrony is a common problem in mechanically ventilated patients. It is associated with adverse effects including increased work of breathing, patient discomfort, increased need for sedation, prolonged mechanical ventilation, weaning difficulties, and weaning failure. The purpose of the present was to describe patient-ventilator asynchrony and its impact on weaning outcomes in mechanically ventilated chronic obstructive pulmonary disease (COPD) patients. Results One hundred mechanically ventilated COPD patients were enrolled in this prospective study. Weaning failure (need of NIV or reintubation within 48 h) was noticed in 27 (27%) patients while 73 (73%) patients had successful weaning. Patients with failed weaning had significantly higher asynchrony index (A.I) and ineffective trigger index (ITI) in comparison with those with successful weaning (7.69 ± 3.71, 3.46 ± 2.59 versus 6.27 ± 3.14, 2.47 ± 2.08, respectively; P value
ISSN:1687-8426
2314-8551
DOI:10.1186/s43168-021-00076-9