Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany

• Published in: BMC public health 2023-01, Vol.23 (1), p.84-84, Article 84
• Main Authors: Tanaka, Luana F, Schoffer, Olaf, König, Jochem, Weyer-Elberich, Veronika, Blettner, Maria, Klug, Stefanie J
• Format: Article
• Language: English
• Subjects: Adult; Aged; Causes of; Demographic aspects; Epidemiology; Female; Forecasts and trends; Germany - epidemiology; Gynaecological surgery; Humans; Hysterectomy; Hysterectomy - methods; Inverse-probability-weighting; Kaplan–Meier; Middle Aged; Missing data; Prevalence; Probability; Proportional Hazards Models
• ISSN: 1471-2458; 1471-2458
• DOI: 10.1186/s12889-022-14916-w

To assess the hysterectomy probability by calendar period and age, the overall and the age-specific prevalence of hysterectomy in women aged 30-65 years. Baseline data (2005-2007) from the population-based MARZY study conducted in Mainz and Mainz-Bingen, Germany, were analysed. 6429 women aged 30-65 years were asked whether they had undergone a hysterectomy and the date and indication of the procedure. We calculated the 5-year age-specific prevalence of hysterectomy and estimated the probability of undergoing a hysterectomy combining two approaches: 1) Kaplan-Meier and 2) Inverse probability weighting (IPW). We assessed potential changes over calendar periods by simulating survival curves, having hysterectomy as the event, employing a Cox proportional hazard model. Data on hysterectomy were available for 4719 women. Of these, 961 (20.4%) had undergone a hysterectomy between 1960 and 2006. The hysterectomy prevalence was highest among the 60-64 year-olds (40.7%). The IPW-corrected probability of having a hysterectomy up to the age of 65 years was 36.4%. The age-specific probability of hysterectomy increased from 0.1% (20-24 years), peaking at 45-49 years (7.8%) and declining thereafter to less than 5% among women aged 50 and older. Over time, women were hysterectomised at an increasingly older age. Most hysterectomies (86.7%) were done due to benign disease. A shift to older age at hysterectomy with an advancing calendar period likely reflects changes in clinical practice in Germany. Landesärztekammer Rheinland-Pfalz: 837.438.03 (4100).