Skin sensitivity – extremely positive reaction for nickelsulfate hexahydrate in association with occupational allergens

• Published in: Nasza dermatologia online 2017-07, Vol.8 (3), p.349-351
• Main Authors: Brambarova, Donka A., Yankova, Rumyana K.
• Format: Article
• Language: English
• Subjects: Allergies; Cosmetics; Dermatitis; Hair; nickelsulfate hexahydrate; Skin
• ISSN: 2081-9390; 2081-9390
• DOI: 10.7241/ourd.20173.99

The subject is healthy at the moment of examination, without any skin lesions and meet the following requirements for testing: good general condition, without serious common diseases and contraindications to conduct testing (acute myocardial infarction, decompensated diabetes, decompensated thyrotoxicosis, renal failure, active tuberculosis, pregnancy), without skin rash (acute and chronic eczema, urticaria, fungal infection, etc.) who do not accept and topically applied drugs affecting the result of testing (corticosteroids, antihistamines, tranquillizers, sympathomimetics). Crescendo phenomenon is specific for allergic reactions and is the main deferens of irritant reactions. Because of the extremely positive and disturbing reaction for Nickelsulfate hexahydrate next readings on 96 hours and on 7 day are not performed. There are seven criteria in our case of Mathias’s seven criteria for confirmation of OCD: 1. the clinical appearance that is consistent with CD; 2. potential culprit cutaneous irritants and/or allergens are present in the workplace; 3. the anatomic distribution of dermatitis is consistent with workplace skin exposure; 4. the temporal relationship between exposure and onset of symptoms is consistent with CD; 5. nonoccupational exposures are excluded as probable causes of the dermatitis; 6. the dermatitis improves when absent from work exposure, and re-exposure results in exacerbation; 7.