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Handgrip strength is associated with risks of new-onset stroke and heart disease: results from 3 prospective cohorts

Stroke and heart disease are two major contributors to the global disease burden. We aimed to evaluate and compare the roles of different handgrip strength (HGS) expressions in predicting stroke and heart disease in three nationally representative cohorts. This longitudinal study used data from the...

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Bibliographic Details
Published in:BMC geriatrics 2023-05, Vol.23 (1), p.268-268, Article 268
Main Authors: Li, Guochen, Lu, Yanqiang, Shao, Liping, Wu, Luying, Qiao, Yanan, Ding, Yi, Ke, Chaofu
Format: Article
Language:English
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Summary:Stroke and heart disease are two major contributors to the global disease burden. We aimed to evaluate and compare the roles of different handgrip strength (HGS) expressions in predicting stroke and heart disease in three nationally representative cohorts. This longitudinal study used data from the Health and Retirement Study (HRS), the Survey of Health, Ageing, and Retirement in Europe (SHARE), and the China Health and Retirement Longitudinal Study (CHARLS). The Cox proportional hazard model was applied to analyze the relationship between HGS and stroke and heart disease, and Harrell's C index was used to assess the predictive abilities of different HGS expressions. A total of 4,407 participants suffered from stroke and 9,509 from heart disease during follow-up. Compared with the highest quartile, participants in the lowest quartile of dominant HGS, absolute HGS and relative HGS possessed a significantly higher risk of new-onset stroke in Europe, America, and China (all P 
ISSN:1471-2318
1471-2318
DOI:10.1186/s12877-023-03953-8