Functional Foods and Adapted Physical Activity as New Adjuvant Therapy for Chronic Kidney Disease Patients

Chronic kidney disease (CKD) will become the fifth leading cause of death in the world by 2040. It is fundamental to prevent and treat this pathology to reduce its impact on national health costs. This trial's aim is to evaluate the effects induced by a combination of consumed functional foods...

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Bibliographic Details
Published in:Nutrients 2024-07, Vol.16 (14), p.2325
Main Authors: Marrone, Giulia, Murri, Arianna, Urciuoli, Silvia, Di Lauro, Manuela, Grazioli, Elisa, Vignolini, Pamela, Cornali, Kevin, Tranchita, Eliana, Masci, Claudia, Cerulli, Claudia, Di Marco, Luca, Mitterhofer, Anna Paola, Parisi, Attilio, Noce, Annalisa
Format: Article
Language:English
Subjects:
Aged
Antioxidants
Antioxidants - administration & dosage
Biomarkers
Body composition
Bone diseases
Cell cycle
circular economy
Comorbidity
Consumption
Diabetes
Exercise
Exercise Therapy - methods
extra virgin olive oil
Female
Food
Functional Food
functional foods
Functional foods & nutraceuticals
Humans
Ingredients
Kidney diseases
Male
Middle Aged
Muscle strength
natural bioactive compounds
non-communicable diseases
Physical fitness
Polyphenols
Proteins
Renal Insufficiency, Chronic - therapy
Sarcopenia
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Summary:Chronic kidney disease (CKD) will become the fifth leading cause of death in the world by 2040. It is fundamental to prevent and treat this pathology to reduce its impact on national health costs. This trial's aim is to evaluate the effects induced by a combination of consumed functional foods (FFs) with adapted physical activity (APA) on the progression of CKD-related comorbidities. The study lasted 12 weeks. We divided 40 CKD patients into four groups: mixed (FF + APA), APA, FF and control group (usual care). The FFs were characterized by their total antioxidant capacity and antiradical activity. The APA was performed though an online training protocol, three times per week, 1 h each session. At the end of the study, we observed, in the mixed group, a decrease in azotemia ( = 0.0272), diastolic blood pressure ( = 0.0169), and C-reactive protein ( = 0.0313), with increases in the FORD test ( = 0.0203) and fat free mass ( = 0.0258). The APA group showed a reduction in total cholesterol ( = 0.0039). The combination of FFs and APA can help counteract several CKD-related comorbidities, such as arterial hypertension, dyslipidemia and uremic sarcopenia, and improve the CKD patients' quality of life.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu16142325