The utility and risks of therapeutic nanotechnology in the retina

The clinical application of nanotechnology in medicine is promising for therapeutic, diagnostic, and surgical improvements in the near future. Nanotechnologies in nano-ophthalmology are in the early stages of application in clinical contexts, including ocular drug and gene delivery systems addressin...

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Bibliographic Details
Published in:Therapeutic Advances in Ophthalmology 2021-01, Vol.13, p.25158414211003381-25158414211003381
Main Authors: Scheive, Melanie, Yazdani, Saeed, Hajrasouliha, Amir R.
Format: Article
Language:English
Subjects:
The Future of Ophthalmology—Novel Tools and Emerging Therapies
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Summary:The clinical application of nanotechnology in medicine is promising for therapeutic, diagnostic, and surgical improvements in the near future. Nanotechnologies in nano-ophthalmology are in the early stages of application in clinical contexts, including ocular drug and gene delivery systems addressing eye disorders, particularly retinopathies. Retinal diseases are challenging to treat as current interventions, such as intravitreal injections, are limited by their invasive nature. This review examines nanotechnological approaches to retinal diseases in a clinical context. Nanotechnology has the potential to transform pharmacological and surgical interventions by overcoming limitations posed by the protective anatomical and physiological barriers that limit access to the retina. Preclinical research in the application of nanoparticles in diagnostics indicates that nanoparticles can enhance existing diagnostic and screening tools to detect diseases earlier and more easily and improve disease progression monitoring precision.
ISSN:2515-8414
2515-8414
DOI:10.1177/25158414211003381