Carapanolides T-X from Carapa guianensis (Andiroba) Seeds

Two new mexicanolide-type limonoids, carapanolides T-U (1-2), and three new phragmalin-type limonoids, carapanolides V-X (3-5), were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D- and 2D-NMR spectroscopy.

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2015-11, Vol.20 (11), p.20955-20966
Main Authors: Miyake, Teppei, Ishimoto, Sari, Ishimatsu, Naoko, Higuchi, Keiichiro, Minoura, Katsuhiko, Kikuchi, Takashi, Yamada, Takeshi, Muraoka, Osamu, Tanaka, Reiko
Format: Article
Language:English
Subjects:
andiroba
Animals
Carapa guianensis
Carbon
Cell Line
Cell Survival - drug effects
Inhibitory Concentration 50
Limonins - chemistry
Limonins - isolation & purification
limonoid
Magnetic Resonance Spectroscopy
Meliaceae
Meliaceae - chemistry
mexicanolide
Mice
Molecular Structure
Nitric Oxide - biosynthesis
NO production
phragmalin
Seeds
Seeds - chemistry
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Summary:Two new mexicanolide-type limonoids, carapanolides T-U (1-2), and three new phragmalin-type limonoids, carapanolides V-X (3-5), were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D- and 2D-NMR spectroscopy.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules201119737