Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media

The utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materi...

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Bibliographic Details
Published in:Catalysts 2020-06, Vol.10 (6), p.697
Main Authors: Alnoch, Robson Carlos, Alves dos Santos, Leandro, Marques de Almeida, Janaina, Krieger, Nadia, Mateo, Cesar
Format: Article
Language:English
Subjects:
Adsorption
Amino acids
biocatalysis
Biocatalysts
Biocompatibility
biomaterials
Biomedical materials
Catalysis
Catalysts
Chemical reactions
Chemical synthesis
Chitin
Chitosan
Enzymes
Functional groups
Immobilization
Lipase
lipases
Molecular biology
non-conventional media
Proteins
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Summary:The utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materials, can be obtained from a wide range of sources and are easy to modify, due to the high variety of functional groups on their surfaces. However, although many lipases have been immobilized on biomaterials and have shown potential for application in biocatalysis, special features are required when the biocatalyst is used in non-conventional media, for example, in organic solvents, which are required for most reactions in organic synthesis. In this article, we discuss the use of biomaterials for lipase immobilization, highlighting recent developments in the synthesis and functionalization of biomaterials using different methods. Examples of effective strategies designed to result in improved activity and stability and drawbacks of the different immobilization protocols are discussed. Furthermore, the versatility of different biocatalysts for the production of compounds of interest in organic synthesis is also described.
ISSN:2073-4344
2073-4344
DOI:10.3390/catal10060697