Scedosporium apiospermum and S. prolificans mixed disseminated infection in a lung transplant recipient: An unusual case of long-term survival with combined systemic and local antifungal therapy in intensive care unit

Infections due Scedosporium spp. in lung transplant recipients are associated with disseminated disease with high mortality rates. The adjunctive local antifungal therapy may be a useful option when systemic treatment is insufficient and/or surgery is not feasible. We present a case of mixed dissemi...

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Bibliographic Details
Published in:Medical mycology case reports 2016-03, Vol.11 (C), p.53-56
Main Authors: Balandin, Bárbara, Aguilar, Miriam, Sánchez, Isabel, Monzón, Araceli, Rivera, Isabel, Salas, Clara, Valdivia, Miguel, Alcántara, Sara, Pérez, Aris, Ussetti, Piedad
Format: Article
Language:English
Subjects:
Case Report
case studies
Disseminated infection
Local antifungal therapy
Long-term survival
Lung transplant recipient
mortality
mycology
Scedosporium
Scedosporium spp
surgery
Synergy test
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Summary:Infections due Scedosporium spp. in lung transplant recipients are associated with disseminated disease with high mortality rates. The adjunctive local antifungal therapy may be a useful option when systemic treatment is insufficient and/or surgery is not feasible. We present a case of mixed disseminated infection due Scedosporium apiospermum and S. prolificans in a lung transplant recipient. Combined local and systemic antifungal therapy provided an unusual long-term survival in the intensive care unit.
ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2016.04.006