Physiologically-based testing system for the mechanical characterization of prosthetic vein valves

Due to the relatively limited amount of work done to date on developing prosthetic vein (as opposed to cardiac) valves, advances in this topic require progress in three distinct areas: 1) improved device design, 2) relevant device testing conditions, and, 3) appropriate parameters for evaluation of...

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Bibliographic Details
Published in:Biomedical engineering online 2007-07, Vol.6 (1), p.29-29
Main Authors: Rittgers, Stanley E, Oberdier, Matt T, Pottala, Sharath
Format: Article
Language:English
Subjects:
Biomechanical Phenomena - instrumentation
Biomechanical Phenomena - methods
Computer Simulation
Computer-Aided Design
Equipment Design - instrumentation
Equipment Design - methods
Equipment Failure Analysis - instrumentation
Equipment Failure Analysis - methods
Heart Valve Prosthesis
Humans
Measurement
Models, Cardiovascular
Testing
Valves
Veins - physiology
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Summary:Due to the relatively limited amount of work done to date on developing prosthetic vein (as opposed to cardiac) valves, advances in this topic require progress in three distinct areas: 1) improved device design, 2) relevant device testing conditions, and, 3) appropriate parameters for evaluation of results. It is the purpose of this paper to address two of these issues (#2 and #3) by: 1) performing a study of normal volunteers to quantify the anatomy and hemodynamic features of healthy venous valves, 2) construction of a 2-step, in vitro testing procedure, which simulates both physiologic and postural conditions seen in the lower extremity venous system, and, 3) defining several modified and new parameters which quantify dynamic valve characteristics.
ISSN:1475-925X
1475-925X
DOI:10.1186/1475-925X-6-29