The impact of palliative radiotherapy on health-related quality of life in patients with head and neck cancer – Results of a multicenter prospective cohort study

•Data on patient-reported outcomes is scarce in palliative radiotherapy for head and neck cancer.•Prospective study with course of quality of life and symptoms as primary objective.•Most analyzable patients had a meaningful improvement of leading symptoms. Palliative radiotherapy for patients with h...

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Published in:Clinical and translational radiation oncology 2023-07, Vol.41, p.100633-100633, Article 100633
Main Authors: Weiss, Marie-Luise, Domschikowski, Justus, Krug, David, Sonnhoff, Mathias, Nitsche, Mirko, Hoffmann, Wolfgang, Becker-Schiebe, Martina, Bock, Felix, Hoffmann, Markus, Schmalz, Claudia, Dunst, Jürgen, Fabian, Alexander
Format: Article
Language:English
Subjects:
Head and neck neoplasms
Original
Palliative care
Patient reported outcome measure
Quality of life
Radiotherapy
Signs and symptoms
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Summary:•Data on patient-reported outcomes is scarce in palliative radiotherapy for head and neck cancer.•Prospective study with course of quality of life and symptoms as primary objective.•Most analyzable patients had a meaningful improvement of leading symptoms. Palliative radiotherapy for patients with head and neck cancer can be used to alleviate symptoms. Only a few studies have investigated its impact on patient-reported outcomes (PRO). Therefore, we conducted a prospective multicenter observational study. The primary objective was to assess changes in health-related quality of life (HrQoL) per PRO. Eligibility criteria included i.) head and neck cancer and ii.) palliative radiotherapy indicated (EQD2Gy 
ISSN:2405-6308
2405-6308
DOI:10.1016/j.ctro.2023.100633