Amenorrhea and elevated βhuman chorionic gonadotropin of unknown origin: An unexpected location of choriocarcinoma

•Amenorrhea and elevated β-hCG could result from an extra genital disease.•Choriocarcinoma may originate primarily in the lungs.•Adjuvant chemotherapy after surgery significantly improves prognosis. Choriocarcinoma is a rare malignancy originating from trophoblastic cells that is known to arise from...

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Bibliographic Details
Published in:Gynecologic oncology reports 2021-05, Vol.36, p.100746, Article 100746
Main Authors: Ben Abdallah, Ichrak, Mlika, Mona, Berrazega, Yosra, Mejri, Nesrine, Rachdi, Haifa, El Benna, Houda, Daoud, Nouha, Laabidi, Soumaya, Mezni, Faouzi, Boussen, Hamouda
Format: Article
Language:English
Subjects:
Amenorrhea
Case Report
Choriocarcinoma
Gestational trophoblastic disease
HCG-beta
Lung neoplasms
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Summary:•Amenorrhea and elevated β-hCG could result from an extra genital disease.•Choriocarcinoma may originate primarily in the lungs.•Adjuvant chemotherapy after surgery significantly improves prognosis. Choriocarcinoma is a rare malignancy originating from trophoblastic cells that is known to arise from the placenta. In this report, we describe the case of a 28-year-old female who consulted for amenorrhea and elevated βhCG mimicking a pregnancy of an unknown location, which ultimately turned out to be primary choriocarcinoma of the lung.
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2021.100746