Evaluation of non-invasive marker of esophageal varices in cirrhosis of liver

Introduction: Esophageal varices develop as a consequence of portal hypertension (PHT) in patients with chronic liver disease. Hence, screening of all cirrhotic patients with upper gastrointestinal endoscopy to detect the presence of significant esophageal varices implies a number of unnecessary end...

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Bibliographic Details
Published in:Journal of family medicine and primary care 2020-02, Vol.9 (2), p.992-996
Main Authors: Kumar, Pardeep, Singh, Kuldeep, Joshi, Arun, Thakur, Priyanka, Mahto, Subodh, Kumar, Brijesh, Pasricha, Nitasha, Patra, Biswa, Lamba, Brinder
Format: Article
Language:English
Subjects:
Analysis
chronic liver disease
clinical
Diagnosis
Diseases
Endoscopy
Esophageal varices
Health screening
hematological markers
Hypertension
Liver
Medical examination
Original
Portal hypertension
radiological markers
Varicose veins
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Summary:Introduction: Esophageal varices develop as a consequence of portal hypertension (PHT) in patients with chronic liver disease. Hence, screening of all cirrhotic patients with upper gastrointestinal endoscopy to detect the presence of significant esophageal varices implies a number of unnecessary endoscopies and has its limitation where such facilities are not available, especially in the rural part of country. Method: Patients with either sex, aged between 18 and 60 years with diagnosis of cirrhosis were studied. Detailed history, physical examination along with relevant investigations were recorded and upper gastrointestinal endoscopy was done within 2-3 days of investigation. Esophageal varices were graded as I-IV, using the Paquet grading system and patients were classified dichotomously either as having large esophageal varices (LEV) group A (Grade III-IV) and no varices group B (grade I-II). Result: A total of 50 patients with cirrhosis of liver were recruited in the study. Among hematological markers, only low platelet count was significantly associated with the presence of LEV (P value
ISSN:2249-4863
2278-7135
DOI:10.4103/jfmpc.jfmpc_854_19