Iron-Based Ceramic Composite Nanomaterials for Magnetic Fluid Hyperthermia and Drug Delivery

Because of the unique physicochemical properties of magnetic iron-based nanoparticles, such as superparamagnetism, high saturation magnetization, and high effective surface area, they have been applied in biomedical fields such as diagnostic imaging, disease treatment, and biochemical separation. Ir...

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Bibliographic Details
Published in:Pharmaceutics 2022-11, Vol.14 (12), p.2584
Main Authors: Chan, Ming-Hsien, Li, Chien-Hsiu, Chang, Yu-Chan, Hsiao, Michael
Format: Article
Language:English
Subjects:
Biocompatibility
Biomedical materials
Cancer therapies
Cell growth
ceramic nanocomposites
Chemical properties
Composite materials
Contrast agents
drug delivery
Drug delivery systems
Drugs
Hyperthermia
Iron
iron-based nanoparticles
Magnetic fields
magnetic fluid hyperthermia
Magnetic properties
Magnetic resonance imaging
Magnetism
Materials research
Nanocomposites
Nanomaterials
Nanoparticles
Nanotechnology
Review
Thermal properties
Thermotherapy
Tumors
Vehicles
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Summary:Because of the unique physicochemical properties of magnetic iron-based nanoparticles, such as superparamagnetism, high saturation magnetization, and high effective surface area, they have been applied in biomedical fields such as diagnostic imaging, disease treatment, and biochemical separation. Iron-based nanoparticles have been used in magnetic resonance imaging (MRI) to produce clearer and more detailed images, and they have therapeutic applications in magnetic fluid hyperthermia (MFH). In recent years, researchers have used clay minerals, such as ceramic materials with iron-based nanoparticles, to construct nanocomposite materials with enhanced saturation, magnetization, and thermal effects. Owing to their unique structure and large specific surface area, iron-based nanoparticles can be homogenized by adding different proportions of ceramic minerals before and after modification to enhance saturation magnetization. In this review, we assess the potential to improve the magnetic properties of iron-based nanoparticles and in the preparation of multifunctional composite materials through their combination with ceramic materials. We demonstrate the potential of ferromagnetic enhancement and multifunctional composite materials for MRI diagnosis, drug delivery, MFH therapy, and cellular imaging applications.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics14122584