MALDI-TOF MS contribution to the diagnosis of Campylobacter rectus multiple skull base and brain abscesses

Abstract Campylobacter rectus is rarely associated with invasive infection. Both the isolation and the identification requirements of C. rectus are fastidious, probably contributing to an underestimation of its burden. We report the case of a 66-year-old man who developed several skull base and intr...

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Bibliographic Details
Published in:New microbes and new infections 2017-09, Vol.19 (C), p.83-86
Main Authors: Martiny, D, Dauby, N, Konopnicki, D, Kampouridis, S, Jissendi Tchofo, P, Horoi, M, Vlaes, L, Retore, P, Hallin, M, Vandenberg, O
Format: Article
Language:English
Subjects:
Campylobacter rectus
Infectious Disease
Intracerebral abscess
MALDI-TOF MS
Mass spectrometry
New Technologies for Infectious and Tropical Diseases
Skull base abscess
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Summary:Abstract Campylobacter rectus is rarely associated with invasive infection. Both the isolation and the identification requirements of C. rectus are fastidious, probably contributing to an underestimation of its burden. We report the case of a 66-year-old man who developed several skull base and intracerebral abscesses after dental intervention. Campylobacter rectus was isolated from the brain biopsy. Within 45 minutes of reading the bacterial plate, the strain was accurately identified by MALDI-TOF MS. This rapid identification avoided the extra costs and delays present with 16S rRNA gene sequencing and allowed for a rapid confirmation of the adequacy of the empirical antibiotic treatment.
ISSN:2052-2975
2052-2975
DOI:10.1016/j.nmni.2017.05.014