Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?

Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area o...

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Bibliographic Details
Published in:Case reports in dermatological medicine 2018, Vol.2018 (2018), p.1-3
Main Authors: Krammer, Caspar Weel, Ibrahim, Rami Mossad
Format: Article
Language:English
Subjects:
Case Report
Case reports
Dermatitis
Dermatology
Inflammation
Lymphatic system
Patients
Pruritus
Radiation
Radiation therapy
Radiotherapy
Scars
Skin
Skin diseases
Throat cancer
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Summary:Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area on a base of irradiated skin which was initially suspected as a skin malignancy. The patient had a history of undifferentiated nasopharyngeal cancer with lymph node involvement which was treated by radiochemotherapy thirteen years previously. Histological examination confirmed that it was a case of prurigo nodularis which subsequently evolved at distant sites. This presentation may suggest a case of an isoradiotopic response.
ISSN:2090-6463
2090-6471
DOI:10.1155/2018/9186745