New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product

Equine serum hepatitis (i.e., Theiler's disease) is a serious and often life-threatening disease of unknown etiology that affects horses. A horse in Nebraska, USA, with serum hepatitis died 65 days after treatment with equine-origin tetanus antitoxin. We identified an unknown parvovirus in seru...

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Bibliographic Details
Published in:Emerging infectious diseases 2018-02, Vol.24 (2), p.303-310
Main Authors: Divers, Thomas J, Tennant, Bud C, Kumar, Arvind, McDonough, Sean, Cullen, John, Bhuva, Nishit, Jain, Komal, Chauhan, Lokendra Singh, Scheel, Troels Kasper Høyer, Lipkin, W Ian, Laverack, Melissa, Trivedi, Sheetal, Srinivasa, Satyapramod, Beard, Laurie, Rice, Charles M, Burbelo, Peter D, Renshaw, Randall W, Dubovi, Edward, Kapoor, Amit
Format: Article
Language:English
Subjects:
Animals
Cardiovirus Infections - veterinary
Cardiovirus Infections - virology
Care and treatment
Drug Contamination
equine liver disease
Female
Hepatitis
Hepatitis, Viral, Animal - virology
horse
Horse Diseases - virology
Horses
metagenomics
New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product
Parvoviridae Infections - veterinary
Parvoviridae Infections - virology
Parvovirinae - genetics
Parvovirinae - isolation & purification
parvovirus
Phylogeny
Prevention
Tetanus
Tetanus antitoxin
Tetanus Antitoxin - adverse effects
Vaccination
Vaccination - adverse effects
veterinary virology
Viremia
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Summary:Equine serum hepatitis (i.e., Theiler's disease) is a serious and often life-threatening disease of unknown etiology that affects horses. A horse in Nebraska, USA, with serum hepatitis died 65 days after treatment with equine-origin tetanus antitoxin. We identified an unknown parvovirus in serum and liver of the dead horse and in the administered antitoxin. The equine parvovirus-hepatitis (EqPV-H) shares
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2402.171031