Effects of Dietary Nitrates on Systemic and Cerebrovascular Hemodynamics

Cerebral blood flow dysregulation is often associated with hypertension. We hypothesized that a beetroot juice (BRJ) treatment could decrease blood pressure and cerebrovascular resistance (CVR). We subjected 12 healthy females to control and BRJ treatments. Cerebrovascular resistance index (CVRI), s...

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Bibliographic Details
Published in:Cardiology Research and Practice 2013-01, Vol.2013 (2013), p.89-97
Main Authors: Bond, Vernon, Curry, Bryan H., Adams, Richard G., Asadi, M. Sadegh, Millis, Richard M., Haddad, Georges E.
Format: Article
Language:English
Subjects:
Aerobics
Automation
Blood pressure
Carbon dioxide
Cerebral circulation
Clinical Study
Ergometry
Exercise
Flow velocity
Gases
Health aspects
Heart rate
Laboratories
Metabolism
Nitrates
Physical fitness
University students
Workloads
Young adults
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Summary:Cerebral blood flow dysregulation is often associated with hypertension. We hypothesized that a beetroot juice (BRJ) treatment could decrease blood pressure and cerebrovascular resistance (CVR). We subjected 12 healthy females to control and BRJ treatments. Cerebrovascular resistance index (CVRI), systolic blood pressure (SBP), total vascular resistance (TVR), and the heart rate-systolic pressure product (RPP) measured at rest and at two exercise workloads were lower after the BRJ treatment. CVRI, SBP, and RPP were lower without a lower TVR at the highest exercise level. These findings suggest improved systemic and cerebral hemodynamics that could translate into a dietary treatment for hypertension.
ISSN:2090-0597
2090-8016
2090-0597
DOI:10.1155/2013/435629