Autoimmune diseases co-existing with hepatitis C virus infection

Autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. Hepatitis C virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the...

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Bibliographic Details
Published in:Iranian journal of allergy, asthma, and immunology asthma, and immunology, 2010-12, Vol.9 (4), p.191-206
Main Authors: Jadali, Zohreh, Alavian, Seyed-Moayed
Format: Article
Language:English
Subjects:
Autoimmune Diseases - complications
Autoimmune Diseases - immunology
Autoimmunity
Endocrine System Diseases - complications
Endocrine System Diseases - immunology
Hematologic Diseases - complications
Hematologic Diseases - immunology
Hepacivirus - immunology
Hepatitis C
Hepatitis C - complications
Hepatitis C - immunology
Hepatitis C Virus
Humans
Idiopathic Pulmonary Fibrosis - complications
Idiopathic Pulmonary Fibrosis - immunology
Immune Mediated Disease
Kidney Diseases - complications
Kidney Diseases - immunology
Nervous System Diseases - complications
Nervous System Diseases - immunology
Rheumatic Diseases - complications
Rheumatic Diseases - immunology
Skin Diseases - complications
Skin Diseases - immunology
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Summary:Autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. Hepatitis C virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis C virus infection and some autoimmune disease has been studied. For some of these disorders their association with hepatitis C virus infection is well recognized while for others it remains probable or weak. Examples of autoimmune phenomena observed in chronic hepatitis C virus infection include rheumatoid arthritis, thyroid disease, cryoglobulinaemia, immune thrombocytopenic purpura, systemic lupus erythematosus and sjogren syndrome. To date, the etiological role and the pathogenetic involvement of the hepatitis C infection remains unknown.The aim of this study is to assess the presence of different autoimmune manifestations of hepatitis C virus infection reported in literature.
ISSN:1735-1502
1735-5249