Evaluation of Cerebrospinal Fluid Pressure by a Formula and Its Role in the Pathogenesis of Glaucoma

Purpose. To investigate potential associations between intraocular pressure (IOP) and cerebrospinal fluid pressure (CSFP) in patients with primary open-angle glaucoma (POAG) and healthy subjects. Methods. Forty-three subjects were recruited. Weight and height were measured to calculate body mass ind...

Full description

Saved in:
Bibliographic Details
Published in:Journal of ophthalmology 2019, Vol.2019 (2019), p.1-6
Main Authors: Iester, Michele, Verticchio Vercellin, Alice C., Harris, Alon, Traverso, Carlo E., Telani, Serena, Casciaro, Federica, Landi, Laura, Saint, Lauren
Format: Article
Language:English
Subjects:
Age
Blood pressure
Body mass index
Cataracts
Cornea
Family medical history
Glaucoma
Heart rate
Hypertension
Optic nerve
Pathogenesis
Risk factors
Standard deviation
Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose. To investigate potential associations between intraocular pressure (IOP) and cerebrospinal fluid pressure (CSFP) in patients with primary open-angle glaucoma (POAG) and healthy subjects. Methods. Forty-three subjects were recruited. Weight and height were measured to calculate body mass index (BMI), along with blood pressure, heart rate, visual acuity, and IOP. Biometrics exam, corneal pachymetry, peripapillary retinal nerve fiber layer (RNFL) thickness, and macular thickness were assessed. The visual field exam was performed on all patients, and both pattern standard deviation (PSD) and mean deviation (MD) were considered. CSFP was estimated indirectly by using the mathematical formula CSFP = 0.44 × BMI + 0.16 × diastolic pressure − 0.18 × age − 1.91, based on the previous scientific studies. The TLCPD was calculated as follows: IOP−CSFP. Results. A significant (p
ISSN:2090-004X
2090-0058
DOI:10.1155/2019/1840481