Cost-effectiveness analysis of seasonal influenza vaccination during pregnancy: A systematic review

Seasonal influenza vaccination is clinically important and reduces hospitalization costs for pregnant women. However, is it also a cost-effective intervention? We conducted a systematic search of Medline (via PUBMED), EMBASE, SCOPUS, and Web of Science databases. We included any economic evaluation...

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Bibliographic Details
Published in:Travel medicine and infectious disease 2023-09, Vol.55, p.102632-102632, Article 102632
Main Authors: Ostad-Ahmadi, Zakieh, Boccalini, Sara, Daemi, Amin, Mahboub-Ahari, Alireza
Format: Article
Language:English
Subjects:
Clinical trials
Content analysis
Cost analysis
Decision trees
Disease control
Economic analysis
Economics
GDP
Gross Domestic Product
Hospitalization
Infectious diseases
Influenza
Intervention
Per capita
Pregnancy
Systematic review
Travel medicine
Vaccination
Vaccines
Women
Womens health
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Summary:Seasonal influenza vaccination is clinically important and reduces hospitalization costs for pregnant women. However, is it also a cost-effective intervention? We conducted a systematic search of Medline (via PUBMED), EMBASE, SCOPUS, and Web of Science databases. We included any economic evaluation studies that reported Incremental Cost-Effectiveness Ratios for vaccinating pregnant women against influenza. Out of 927 potentially eligible articles, only 14 full texts met our inclusion criteria. In almost all studies, vaccinating pregnant women was a cost-effective and cost-saving strategy. In one study, it was not cost-effective when the researchers used costs and probabilities related to other groups (healthy adults) due to the lack of data for pregnant women. The main factors influencing the cost-effectiveness of the studies were vaccine efficacy and vaccination cost. Influenza vaccination of pregnant women is a cost-effective intervention. More studies on the cost-effectiveness of this intervention in underdeveloped countries are needed. pregnancy, cost-effectiveness, cost-utility, cost-benefit, influenza vaccine, women, economic evaluation.
ISSN:1477-8939
1873-0442
DOI:10.1016/j.tmaid.2023.102632