Acute Pain Burden and Opioid Dose Requirements after Cesarean Delivery in Parturients with Preexisting Chronic Back Pain and Migraine

Introduction. Preexisting chronic pain has been reported to be a consistent risk factor for severe acute postoperative pain. However, each specific chronic pain condition has unique pathophysiology, and it is possible that the effect of each condition on postoperative pain is different. Methods. Thi...

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Published in:Anesthesiology research and practice 2021, Vol.2021, p.3305579-6
Main Authors: Komatsu, Ryu, Nash, Michael G., Ruth, Kenneth C., Harbour, William, Ziga, Taylor M., Mandalia, Shane, Dinges, Emily M., Singh, Davin, El-Omrani, Hani, Reno, Joseph, Carvalho, Brendan, Bollag, Laurent A.
Format: Article
Language:English
Subjects:
Backache
Cesarean section
Chronic pain
Migraine
Morphine
Pregnant women
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Summary:Introduction. Preexisting chronic pain has been reported to be a consistent risk factor for severe acute postoperative pain. However, each specific chronic pain condition has unique pathophysiology, and it is possible that the effect of each condition on postoperative pain is different. Methods. This is a retrospective cohort study of pregnant women with preexisting chronic pain conditions (i.e., migraine, chronic back pain, and the combination of migraine + chronic back pain), who underwent cesarean delivery. The effects of the three chronic pain conditions on time-weighted average (TWA) pain score (primary outcome) and opioid dose requirements in morphine milligram equivalents (MME) during postoperative 48 hours were compared. Results. The TWA pain score was similar in preexisting migraine and chronic back pain. Chronic back pain was associated with significantly greater opioid dose requirements than migraine (12.92 MME, 95% CI: 0.41 to 25.43, P=0.041). Preoperative opioid use (P
ISSN:1687-6962
1687-6970
DOI:10.1155/2021/3305579