Comparison of the changes in the factors associated with the renal prognosis of non-elderly and elderly subjects treated with empagliflozin- a retrospective observation study in Japanese patients with type 2 diabetes

The factors associated with the renal prognosis over six months after the initiation of empagliflozin were compared between the non-elderly and elderly Japanese patients with type 2 diabetes. In total, 132 patients treated with empagliflozin (10 mg, once daily) were studied as the safety analysis se...

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Published in:Diabetes, metabolic syndrome and obesity metabolic syndrome and obesity, 2019-09, Vol.12, p.1783-1794
Main Authors: Ito, Hiroyuki, Matsumoto, Suzuko, Izutsu, Takuma, Kusano, Eiji, Nishio, Shinya, Antoku, Shinichi, Yamasaki, Tomoko, Mori, Toshiko, Togane, Michiko, Ando, Shigenori, Tsugami, Emiko
Format: Article
Language:English
Subjects:
Age
Blood pressure
Body weight
Cardiovascular disease
Comparative analysis
Diabetes
Diabetes mellitus
Diabetic retinopathy
elderly
Elderly patients
Empagliflozin
Ezetimibe
Glucose
Glycosylated hemoglobin
Heart failure
Hemoglobins
Hypertension
Kidney diseases
Medical prognosis
Medical research
Metabolism
Original Research
Patients
Prognosis
renal impairment
renoprotection
sodium-glucose cotransporter 2 inhibitor
Type 2 diabetes
type 2 diabetes mellitus
Urine
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Summary:The factors associated with the renal prognosis over six months after the initiation of empagliflozin were compared between the non-elderly and elderly Japanese patients with type 2 diabetes. In total, 132 patients treated with empagliflozin (10 mg, once daily) were studied as the safety analysis set. One hundred ten subjects whose medications were not changed during the observation period were investigated as the full analysis set to assess the effectiveness. The subjects were divided into two groups: non-elderly subjects (n=72) of
ISSN:1178-7007
1178-7007
DOI:10.2147/DMSO.S221655