Magnetic resonance tractography exhibiting retrograde degeneration of the corticospinal tract in a patient with a unilateral spinal cord tumor

• Published in: Brain and behavior 2021-04, Vol.11 (4), p.e02020-n/a
• Main Authors: Osaki, Yusuke, Sako, Wataru, Harada, Masafumi, Izumi, Yuishin
• Format: Article
• Language: English
• Subjects: Alzheimer's disease; Cancer; Comorbidity; corticospinal tracts; diffusion tractography; Gait; Magnetic resonance imaging; Nervous system; Original Research; Pathology; Patients; retrograde degeneration; Spinal cancer; Spinal cord; Spinal cord injuries; spinal cord neoplasms
• ISSN: 2162-3279; 2162-3279
• DOI: 10.1002/brb3.2020

Background Transection‐induced axonal retrograde degeneration, in contrast to Wallerian degeneration, has not been widely recognized in clinical practice. Aims of the Study To assess a potential of corticospinal tractography for detecting axonal retrograde degeneration. Methods We assessed the corticospinal tractography of a 74‐year‐old woman with monoplegia of the lower limb due to a unilateral thoracic spinal cord tumor. Results The tractography revealed integrity reduction of the corticospinal tract in the cerebra contralateral to the spinal cord tumor. Conclusions The present report supports that magnetic resonance tractography has the potential for detecting this under‐recognized phenomenon. To assess a potential of corticospinal tractography for detecting axonal retrograde degeneration, an under‐recognized phenomenon, we performed the cerebral corticospinal tractography of a 74‐year‐old woman with monoplegia of the lower limb due to a unilateral thoracic spinal cord tumor. The tractography revealed integrity reduction of the corticospinal tract in the cerebra contralateral to the spinal cord tumor. The present report supports that magnetic resonance tractography has the potential for detecting this under‐recognized phenomenon.