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Post Autologous Bone Marrow Transplant Associated With a Resultant Mixed Polyclonal/Monoclonal Hyper-IgG3

There have been few studies illustrating the post immunological phenotype of patients receiving autologous bone marrow transplant (ABMT) for the treatment of diffuse large B-cell lymphoma. High-dose chemotherapy and autologous bone marrow transplantation have been shown to be the only potential cura...

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Bibliographic Details
Published in:Allergy & rhinology (Providence, R.I.) R.I.), 2020-01, Vol.11, p.2152656720915701-2152656720915701
Main Authors: Fill, Lauren, Rowane, Marija, Graven, Kelsey, Sanan, Neha, Wu, Shan Shan, Hostoffer, Robert W.
Format: Article
Language:English
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Summary:There have been few studies illustrating the post immunological phenotype of patients receiving autologous bone marrow transplant (ABMT) for the treatment of diffuse large B-cell lymphoma. High-dose chemotherapy and autologous bone marrow transplantation have been shown to be the only potential curative treatment modalities for B-cell lymphoma. Autologous bone marrow transplantation, although widely utilized in patients with non-Hodgkin lymphoma recurrence, does have an association with immunologic side effects, although serologic changes where rarely reported unless accompanied by recurrent infections. We report the first case of a 62-year-old female patient who experienced recurrent infections, namely, sinusitis and pneumonia, after receiving an ABMT with subsequent hyper-IgG3 phenotype
ISSN:2152-6567
2152-6575
2152-6567
DOI:10.1177/2152656720915701