Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade

To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane (ILM) peeling with or without gas tamponade for highly myopic foveoschisis. We performed an open-label, observer-blinded clinical trial of 85 patients with myopic foveoschisis between 2000 and 2012. Patients w...

Full description

Saved in:
Bibliographic Details
Published in:International journal of ophthalmology 2017-09, Vol.10 (9), p.1392-1395
Main Authors: Yun, Li-Na, Xing, Yi-Qiao
Format: Article
Language:English
Subjects:
1395
Clinical Research
gas tamponade
internal limiting membrane peeling
myopic foveoschisis
vitrectomy
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c459t-5c0806ac11cabfa29f26dcdfa20d49ba4115bc487ccbafc09fa65fc008d226c23
cites
container_end_page 1395
container_issue 9
container_start_page 1392
container_title International journal of ophthalmology
container_volume 10
creator Yun, Li-Na
Xing, Yi-Qiao
description To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane (ILM) peeling with or without gas tamponade for highly myopic foveoschisis. We performed an open-label, observer-blinded clinical trial of 85 patients with myopic foveoschisis between 2000 and 2012. Patients were randomly allocated to one of two groups, those who received vitrectomy and ILM peeling without gas tamponade (no-gas group) or those who with gas tamponade (gas group) and follow up at least 5y. Visual acuity of gas group improved from 0.82±0.33 to 0.79±0.73 in 6mo, improved to 0.71±0.67 in 1y and within this range in the following 4y. Visual acuity of no-gas group improved from 0.81±0.46 to 0.78±0.66 in 6mo, improved to 0.70±0.65 in 1y. The finial visual acuity of two groups were significantly increased compared with the baseline (
doi_str_mv 10.18240/ijo.2017.09.10
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_7e881ddc62cb4f5bbf6ca7f36e050f52</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_7e881ddc62cb4f5bbf6ca7f36e050f52</doaj_id><sourcerecordid>1942714714</sourcerecordid><originalsourceid>FETCH-LOGICAL-c459t-5c0806ac11cabfa29f26dcdfa20d49ba4115bc487ccbafc09fa65fc008d226c23</originalsourceid><addsrcrecordid>eNpVkc9rHCEUx4fS0oQ0596Kx15mo646eimU0B-BhV7aszhPnXGZGbfqbpn_vmY3DY0I3-fz-z4K36Z5T_CGSMrwXdjHDcWk22C1IfhVc00p7VomlXx9rmm7VVxdNbc573FdgmOC2dvmikrFGFHyuoFdXIa2uDSjeCwQZ4eiR2MYxmlF8xoPAZCPJxczjCGHjEpypjiL-hWdQj1AifOK_oQyopjOWjloMNVp5kNcjHXvmjfeTNndPulN8-vrl5_339vdj28P9593LTCuSssBSywMEAKm94YqT4UFWytsmeoNI4T3wGQH0BsPWHkjeFUsLaUC6PamebhwbTR7fUhhNmnV0QR9bsQ0aJNKgMnpzklJrAVBoWee970XYDq_FQ5z7Pkj69OFdTj2s7PglpLM9AL68mYJox7iSXOuBKWsAj4-AVL8fXS56DlkcNNkFhePWRPFaEdY3dV6d7FCijkn55-fIVifk9Y1af2YtMaqNuvEh_9_9-z_l-v2L_CEqJo</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1942714714</pqid></control><display><type>article</type><title>Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade</title><source>PubMed (Medline)</source><creator>Yun, Li-Na ; Xing, Yi-Qiao</creator><creatorcontrib>Yun, Li-Na ; Xing, Yi-Qiao</creatorcontrib><description>To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane (ILM) peeling with or without gas tamponade for highly myopic foveoschisis. We performed an open-label, observer-blinded clinical trial of 85 patients with myopic foveoschisis between 2000 and 2012. Patients were randomly allocated to one of two groups, those who received vitrectomy and ILM peeling without gas tamponade (no-gas group) or those who with gas tamponade (gas group) and follow up at least 5y. Visual acuity of gas group improved from 0.82±0.33 to 0.79±0.73 in 6mo, improved to 0.71±0.67 in 1y and within this range in the following 4y. Visual acuity of no-gas group improved from 0.81±0.46 to 0.78±0.66 in 6mo, improved to 0.70±0.65 in 1y. The finial visual acuity of two groups were significantly increased compared with the baseline ( &lt;0.05). The visual acuity was improved in 35 of 40 eyes (87.5%) in gas group and 29 of 33 eyes (87.9%) in no-gas group, while there were no significant differences between gas group and no-gas group in the visual acuity. The foveoschisis on optical coherence tomography (OCT) completely resolved in 5 of 40 eyes in 1mo, 14 eyes in 6mo and 40 eyes in 1y in the gas group. While the foveoschisis completely resolved in 4 of 33 eyes in 1mo, 10 eyes in 6mo and 33 eyes in 1y in the no-gas group. Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy and ILM with gas tamponade. However, eyes treated with no-gas tamponade showed more rapid resolution of myopic foveoschisis.</description><identifier>ISSN: 2222-3959</identifier><identifier>EISSN: 2227-4898</identifier><identifier>DOI: 10.18240/ijo.2017.09.10</identifier><identifier>PMID: 28944198</identifier><language>eng</language><publisher>China: International Journal of Ophthalmology Press</publisher><subject>1395 ; Clinical Research ; gas tamponade ; internal limiting membrane peeling ; myopic foveoschisis ; vitrectomy</subject><ispartof>International journal of ophthalmology, 2017-09, Vol.10 (9), p.1392-1395</ispartof><rights>International Journal of Ophthalmology Press 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-5c0806ac11cabfa29f26dcdfa20d49ba4115bc487ccbafc09fa65fc008d226c23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596224/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596224/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28944198$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yun, Li-Na</creatorcontrib><creatorcontrib>Xing, Yi-Qiao</creatorcontrib><title>Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade</title><title>International journal of ophthalmology</title><addtitle>Int J Ophthalmol</addtitle><description>To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane (ILM) peeling with or without gas tamponade for highly myopic foveoschisis. We performed an open-label, observer-blinded clinical trial of 85 patients with myopic foveoschisis between 2000 and 2012. Patients were randomly allocated to one of two groups, those who received vitrectomy and ILM peeling without gas tamponade (no-gas group) or those who with gas tamponade (gas group) and follow up at least 5y. Visual acuity of gas group improved from 0.82±0.33 to 0.79±0.73 in 6mo, improved to 0.71±0.67 in 1y and within this range in the following 4y. Visual acuity of no-gas group improved from 0.81±0.46 to 0.78±0.66 in 6mo, improved to 0.70±0.65 in 1y. The finial visual acuity of two groups were significantly increased compared with the baseline ( &lt;0.05). The visual acuity was improved in 35 of 40 eyes (87.5%) in gas group and 29 of 33 eyes (87.9%) in no-gas group, while there were no significant differences between gas group and no-gas group in the visual acuity. The foveoschisis on optical coherence tomography (OCT) completely resolved in 5 of 40 eyes in 1mo, 14 eyes in 6mo and 40 eyes in 1y in the gas group. While the foveoschisis completely resolved in 4 of 33 eyes in 1mo, 10 eyes in 6mo and 33 eyes in 1y in the no-gas group. Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy and ILM with gas tamponade. However, eyes treated with no-gas tamponade showed more rapid resolution of myopic foveoschisis.</description><subject>1395</subject><subject>Clinical Research</subject><subject>gas tamponade</subject><subject>internal limiting membrane peeling</subject><subject>myopic foveoschisis</subject><subject>vitrectomy</subject><issn>2222-3959</issn><issn>2227-4898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkc9rHCEUx4fS0oQ0596Kx15mo646eimU0B-BhV7aszhPnXGZGbfqbpn_vmY3DY0I3-fz-z4K36Z5T_CGSMrwXdjHDcWk22C1IfhVc00p7VomlXx9rmm7VVxdNbc573FdgmOC2dvmikrFGFHyuoFdXIa2uDSjeCwQZ4eiR2MYxmlF8xoPAZCPJxczjCGHjEpypjiL-hWdQj1AifOK_oQyopjOWjloMNVp5kNcjHXvmjfeTNndPulN8-vrl5_339vdj28P9593LTCuSssBSywMEAKm94YqT4UFWytsmeoNI4T3wGQH0BsPWHkjeFUsLaUC6PamebhwbTR7fUhhNmnV0QR9bsQ0aJNKgMnpzklJrAVBoWee970XYDq_FQ5z7Pkj69OFdTj2s7PglpLM9AL68mYJox7iSXOuBKWsAj4-AVL8fXS56DlkcNNkFhePWRPFaEdY3dV6d7FCijkn55-fIVifk9Y1af2YtMaqNuvEh_9_9-z_l-v2L_CEqJo</recordid><startdate>20170918</startdate><enddate>20170918</enddate><creator>Yun, Li-Na</creator><creator>Xing, Yi-Qiao</creator><general>International Journal of Ophthalmology Press</general><general>Press of International Journal of Ophthalmology (IJO PRESS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20170918</creationdate><title>Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade</title><author>Yun, Li-Na ; Xing, Yi-Qiao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-5c0806ac11cabfa29f26dcdfa20d49ba4115bc487ccbafc09fa65fc008d226c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>1395</topic><topic>Clinical Research</topic><topic>gas tamponade</topic><topic>internal limiting membrane peeling</topic><topic>myopic foveoschisis</topic><topic>vitrectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yun, Li-Na</creatorcontrib><creatorcontrib>Xing, Yi-Qiao</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>International journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yun, Li-Na</au><au>Xing, Yi-Qiao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade</atitle><jtitle>International journal of ophthalmology</jtitle><addtitle>Int J Ophthalmol</addtitle><date>2017-09-18</date><risdate>2017</risdate><volume>10</volume><issue>9</issue><spage>1392</spage><epage>1395</epage><pages>1392-1395</pages><issn>2222-3959</issn><eissn>2227-4898</eissn><abstract>To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane (ILM) peeling with or without gas tamponade for highly myopic foveoschisis. We performed an open-label, observer-blinded clinical trial of 85 patients with myopic foveoschisis between 2000 and 2012. Patients were randomly allocated to one of two groups, those who received vitrectomy and ILM peeling without gas tamponade (no-gas group) or those who with gas tamponade (gas group) and follow up at least 5y. Visual acuity of gas group improved from 0.82±0.33 to 0.79±0.73 in 6mo, improved to 0.71±0.67 in 1y and within this range in the following 4y. Visual acuity of no-gas group improved from 0.81±0.46 to 0.78±0.66 in 6mo, improved to 0.70±0.65 in 1y. The finial visual acuity of two groups were significantly increased compared with the baseline ( &lt;0.05). The visual acuity was improved in 35 of 40 eyes (87.5%) in gas group and 29 of 33 eyes (87.9%) in no-gas group, while there were no significant differences between gas group and no-gas group in the visual acuity. The foveoschisis on optical coherence tomography (OCT) completely resolved in 5 of 40 eyes in 1mo, 14 eyes in 6mo and 40 eyes in 1y in the gas group. While the foveoschisis completely resolved in 4 of 33 eyes in 1mo, 10 eyes in 6mo and 33 eyes in 1y in the no-gas group. Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy and ILM with gas tamponade. However, eyes treated with no-gas tamponade showed more rapid resolution of myopic foveoschisis.</abstract><cop>China</cop><pub>International Journal of Ophthalmology Press</pub><pmid>28944198</pmid><doi>10.18240/ijo.2017.09.10</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2222-3959
ispartof International journal of ophthalmology, 2017-09, Vol.10 (9), p.1392-1395
issn 2222-3959
2227-4898
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_7e881ddc62cb4f5bbf6ca7f36e050f52
source PubMed (Medline)
subjects 1395
Clinical Research
gas tamponade
internal limiting membrane peeling
myopic foveoschisis
vitrectomy
title Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T17%3A30%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Long-term%20outcome%20of%20highly%20myopic%20foveoschisis%20treated%20by%20vitrectomy%20with%20or%20without%20gas%20tamponade&rft.jtitle=International%20journal%20of%20ophthalmology&rft.au=Yun,%20Li-Na&rft.date=2017-09-18&rft.volume=10&rft.issue=9&rft.spage=1392&rft.epage=1395&rft.pages=1392-1395&rft.issn=2222-3959&rft.eissn=2227-4898&rft_id=info:doi/10.18240/ijo.2017.09.10&rft_dat=%3Cproquest_doaj_%3E1942714714%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c459t-5c0806ac11cabfa29f26dcdfa20d49ba4115bc487ccbafc09fa65fc008d226c23%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1942714714&rft_id=info:pmid/28944198&rfr_iscdi=true