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Development of rheumatoid arthritis during treatment of multiple sclerosis with interferon beta 1-a. Coincidence of two conditions or a complication of treatment: A case report

Coexistence of multiple sclerosis (MS) with other autoimmune diseases has been attributed to common background genetic or environmental factors. This study presents development of rheumatoid arthritis (RA) during treatment of MS. The MS was confirmed by the Mc Donald criteria and the diagnosis of RA...

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Bibliographic Details
Published in:Journal of advanced research 2016-09, Vol.7 (5), p.611-613
Main Authors: Hojjati, Seyed Mohammad Masood, Heidari, Behzad, Babaei, Mansour
Format: Article
Language:English
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Summary:Coexistence of multiple sclerosis (MS) with other autoimmune diseases has been attributed to common background genetic or environmental factors. This study presents development of rheumatoid arthritis (RA) during treatment of MS. The MS was confirmed by the Mc Donald criteria and the diagnosis of RA was confirmed by the ACR/EULAR criteria. A 35years old women with 9years of MS who was receiving interferon beta 1-a (INF) for 7years and who did not respond to conventional therapy of RA over 8months developed clinical manifestations of RA. But a rapid response was observed after discontinuation of INF. These findings suggest a possible contribution of INF in the development of RA.
ISSN:2090-1232
2090-1224
DOI:10.1016/j.jare.2016.06.004