Interaction of Various Variants of the Nanostructured Surface of Titanium with MSCs Isolated from Adipose Tissue

Titanium has been successfully used in dental implantology for a long time. Due to the osseointegration process, titanium implants are able to withstand the chewing load. This article is devoted to the study of surface treatment methods of titanium alloys and the study of their interaction with mese...

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Bibliographic Details
Published in:Biomimetics (Basel, Switzerland) Switzerland), 2021-10, Vol.6 (4), p.61
Main Authors: Gosteva, Ekaterina A., Dymnikov, Alexander B., Starkov, Vitaliy V., Sedlovets, Daria M., Valikhov, Marat P., Vishnevsky, Dmytryi A., Chekhonin, Vladimir P., Tumanyan, Gurgen A., Ahmad, Masound K.
Format: Article
Language:English
Subjects:
Adipose tissue
Alloys
Biocompatibility
Body fat
chemical etching
Chemical vapor deposition
Dental implants
Dental prosthetics
denture
Etching
Graphene
graphene-like films
Mesenchymal stem cells
Mesenchyme
Morphology
Osseointegration
Stem cells
Titanium
Titanium alloys
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Summary:Titanium has been successfully used in dental implantology for a long time. Due to the osseointegration process, titanium implants are able to withstand the chewing load. This article is devoted to the study of surface treatment methods of titanium alloys and the study of their interaction with mesenchymal stem cells (MSCs). The surface microrelief can influence MSC differentiation in different ways, which subsequently gives it osteogenic potential. The paper proposes modes of surface modification of titanium alloys on Grade 4 and Grade 1 by chemical and electrochemical (anodizing) etching. The possibility of modifying the surface of titanium alloys using the synthesis of graphene layers has been proposed in this paper for the first time. The osteogenic potential of a particular surface was assessed by the number of mesenchymal stem cells cultured on them under identical conditions.
ISSN:2313-7673
2313-7673
DOI:10.3390/biomimetics6040061