Medication-related osteonecrosis of the jaw in a patient with multiple myeloma

Osteonecrosis of jaws is a common complication of parenteral nitrogen-containing bisphosphonates and recently medication-related osteonecrosis of the jaw (MRONJ) is contributing to the growing number of similar osteonecrosis cases which involve maxilla and mandible associated with other anti-resorpt...

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Bibliographic Details
Published in:Journal of Indian Academy of Oral Medicine and Radiology 2015-10, Vol.27 (4), p.576-579
Main Authors: Bhardwaj, Nupur, Daniel, Mariappan, Srinivasan, Subramanian, Jimsha, Vannathan
Format: Article
Language:English
Subjects:
Care and treatment
Case studies
Chemotherapy
Health aspects
Medication-related osteonecrosis of the jaw
Multiple myeloma
Osteonecrosis
Risk factors
zoledronate
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Summary:Osteonecrosis of jaws is a common complication of parenteral nitrogen-containing bisphosphonates and recently medication-related osteonecrosis of the jaw (MRONJ) is contributing to the growing number of similar osteonecrosis cases which involve maxilla and mandible associated with other anti-resorptive and anti-angiogenic therapies. A 70-year-old male patient with multiple myeloma and discontinued chemotherapy reported with non-healing extraction site for past 1 year. He also complained of pus discharge extraorally for past 3 months. This case report describes the imaging findings of multiple myeloma in mandible and MRONJ.
ISSN:0972-1363
0975-1572
DOI:10.4103/0972-1363.188766