Flavanone Glycosides, Triterpenes, Volatile Compounds and Antimicrobial Activity of Miconia minutiflora (Bonpl.) DC. ( Melastomataceae )

• Published in: Molecules (Basel, Switzerland) Switzerland), 2022-03, Vol.27 (6), p.2005
• Main Authors: Ferreira, Nathália Siso, Cascaes, Márcia Moraes, da Silva Santos, Lourivaldo, de Oliveira, Mozaniel Santana, das Graças Bichara Zoghbi, Maria, Araújo, Isabella Santos, Uetanabaro, Ana Paula Trovatti, de Aguiar Andrade, Eloisa Helena, Guilhon, Giselle Maria Skelding Pinheiro
• Format: Article
• Language: English
• Subjects: Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; antimicrobial assays; Chemical composition; E coli; Essential oils; Fatty acids; Flavanones - pharmacology; Gallic acid; Glucose; Glycosides; Glycosides - pharmacology; Melastomataceae - chemistry; Miconia; Microorganisms; Monoterpenes; Oils & fats; Phenols; pinocembroside; pinocembroside derivative; Steroids; Triterpenes; ursolic acid; Volatile compounds
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules27062005

Chemical composition of the essential oils and extracts and the antimicrobial activity of Miconia minutiflora were investigated. The flavanone glycosides, pinocembroside and pinocembrin-7-O-[4″,6″-HHDP]-β-D-glucose, were identified, along with other compounds that belong mainly to the triterpene class, besides the phenolics, gallic acid and methyl gallate. Sesquiterpenes and monoterpenes were the major compounds identified from the essential oils. Screening for antimicrobial activity from the methanolic extract of the leaves showed that the MIC and MMC values against the tested microorganisms ranged from 0.625 to 5 mg·mL−1 and that the extract was active against microorganisms, Staphyloccocus aureus, Escherichia coli, and Bacillus cereus.