A Significant Association of Upper Limb Muscle Strength with Thyroid Function in Overweight and Obese Population: A Study of the Sixth Korea National Health and Nutrition Examination Survey (KNHANES 2014-2015)

Background. As skeletal muscle is one of main targets of thyroid hormone signalling, an association of thyroid function and muscle strength could be expected. The aim of study is to evaluate the association of free thyroxine (FT4) and thyrotropin (TSH) with upper limb muscle strength, measured by ha...

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Bibliographic Details
Published in:International journal of endocrinology 2020, Vol.2020 (2020), p.1-8
Main Authors: Kim, Min-Hee, Chang, Sang-Ah, Lee, Jung Min, Lim, Dong-Jun, Ha, Jeonghoon, Jo, Kwanhoon, Lee, Jeongmin, Kang, Moo Il
Format: Article
Language:English
Subjects:
Age
Body mass index
Diabetes
Endocrinology
Exercise
Health surveys
Metabolism
Muscle function
Muscle strength
Muscles
Musculoskeletal system
Nutrition
Nutritional status
Obesity
Overweight
Physical fitness
Population
Risk factors
Sample size
Sarcopenia
Thyroid diseases
Thyroid gland
Thyrotropin
Thyroxine
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Summary:Background. As skeletal muscle is one of main targets of thyroid hormone signalling, an association of thyroid function and muscle strength could be expected. The aim of study is to evaluate the association of free thyroxine (FT4) and thyrotropin (TSH) with upper limb muscle strength, measured by hand grip strength, in subjects with normal FT4 from national representative data. The study utilized the sixth edition of the Korea National Health and Nutrition Examination Survey. After exclusion of subjects with FT4 level out of normal range, a history of thyroid disease or cerebral disease, restricted activity, and incomplete data, a total of 3503 were recruited (age range 19–80 years, 51% male). FT4 positively correlated with upper limb muscle strength (β coefficient = −12.84, p
ISSN:1687-8337
1687-8345
DOI:10.1155/2020/7195846