The Association of Serum Lipid Levels with Breast Cancer Risks Among Women with Breast Cancer at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia

Breast cancer is a malignant condition affecting about 2.1 million women worldwide. Cancer cells have increased the level of cholesterol and facilitate lipid biosynthesis and metabolism. Therefore, there is a need for assessment of serum lipid and its association with breast cancer risks. A comparat...

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Bibliographic Details
Published in:Breast cancer targets and therapy 2020-01, Vol.12, p.279-287
Main Authors: Kumie, Getinet, Melak, Tadele, Wondifraw Baynes, Habtamu
Format: Article
Language:English
Subjects:
Age
Alcohol use
Benign
Blood pressure
Breast cancer
Breastfeeding & lactation
Cancer
Cancer therapies
Cholesterol
Colorimetry
Comparative analysis
Drinking behavior
Dyslipidemia
Enzymes
ethiopia
Family medical history
Health care
High density lipoprotein
Hypertension
Lipid metabolism
lipid profile
Lipids
Lipoproteins
Low density lipoprotein
Low density lipoproteins
Menstruation
Metabolic disorders
Oncology, Experimental
Original Research
Patients
Physiological aspects
Risk factors
Sociodemographics
Statistical analysis
Tumor necrosis factor-TNF
women
Womens health
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Summary:Breast cancer is a malignant condition affecting about 2.1 million women worldwide. Cancer cells have increased the level of cholesterol and facilitate lipid biosynthesis and metabolism. Therefore, there is a need for assessment of serum lipid and its association with breast cancer risks. A comparative cross-sectional study was conducted among women with breast cancer (n=23), benign breast lump (n=68) and apparently healthy control (n=91) at Felege Hiwot Comprehensive Specialized Hospital, from January to May, 2020. A convenient sampling technique and an interviewer-administered questionnaires were used to collect data. Five milliliter of fasting blood sample was collected for lipid level analysis using enzymatic colorimetric method. Data entry and analysis were done using Epi Info version 7 and SPSS version 20. One way ANOVA and logistic regression were the tools used for analysis, and a p-value of
ISSN:1179-1314
1179-1314
DOI:10.2147/BCTT.S279291